Hepatic Cecum: a Key Integrator of Immunity in Amphioxus

Overview

Journal Mar Life Sci Technol

Date 2023 Apr 19

PMID 37073295

Authors

Baozhen Qu

Shicui Zhang

Zengyu Ma

Zhan Gao

Affiliations

Soon will be listed here.

Abstract

The vertebrate liver is regarded as an organ essential to the regulation of immunity and inflammation as well as being central to the metabolism of nutrients. Here, we discuss the functions that the hepatic cecum of amphioxus plays in the regulation of immunity and inflammation, and the molecular basis of this. It is apparent that the hepatic cecum performs important roles in the immunity of amphioxus including immune surveillance, clearance of pathogens and acute phase response. Therefore, the hepatic cecum, like the vertebrate liver, is an organ functioning as a key integrator of immunity in amphioxus.

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