Factors Associated with Acute Kidney Injury in Patients Undergoing Extracorporeal Membrane Oxygenation: Retrospective Cohort

Overview

Journal Rev Esc Enferm USP

Specialties Medical Education
Nursing

Date 2023 Apr 18

PMID 37071796

Authors

Filipe Utuari de Andrade Coelho

Barbara Gadioli

Flavia Fernandes Manfredi de Freitas

Maria de Fatima Fernandes Vattimo

Affiliations

Soon will be listed here.

Abstract

Objective: To identify factors associated with acute kidney injury in patients undergoing extracorporeal membrane oxygenation.

Method: Retrospective cohort study conducted in an adult Intensive Care Unit with patients undergoing extracorporeal membrane oxygenation from 2012 to 2021. The research used the Kidney Disease Improving Global Outcomes as criteria for definition and classification of acute kidney injury. A multiple logistic regression model was developed to analyze the associated factors.

Results: The sample was composed of 122 individuals, of these, 98 developed acute kidney injury (80.3%). In multiple regression, the associated factors found were vasopressin use, Nursing Activities Score, and glomerular filtration rate.

Conclusion: The use of vasopressin, the Nursing Activities Score, and the glomerular filtration rate were considered as factors related to the development of acute kidney injury in patients undergoing extracorporeal membrane oxygenation.

Citing Articles

Prognostic Scores for Acute Kidney Injury in Critically Ill Patients.

Sousa W, Magro M, Paiva A, Vasconcelos R, Dos Reis A, Lima W Nurs Rep. 2024; 14(4):3619-3630.

PMID: 39585155 PMC: 11587434. DOI: 10.3390/nursrep14040264.

References

Abu Alfeilat M, Slotki I, Shavit L . Single emergency room measurement of neutrophil/lymphocyte ratio for early detection of acute kidney injury (AKI). Intern Emerg Med. 2017; 13(5):717-725. DOI: 10.1007/s11739-017-1715-8. View

Thongprayoon C, Cheungpasitporn W, Lertjitbanjong P, Aeddula N, Bathini T, Watthanasuntorn K . Incidence and Impact of Acute Kidney Injury in Patients Receiving Extracorporeal Membrane Oxygenation: A Meta-Analysis. J Clin Med. 2019; 8(7). PMC: 6678289. DOI: 10.3390/jcm8070981. View

Lowe R, Ferrari M, Nasim-Mohi M, Jackson A, Beecham R, Veighey K . Clinical characteristics and outcome of critically ill COVID-19 patients with acute kidney injury: a single centre cohort study. BMC Nephrol. 2021; 22(1):92. PMC: 7957445. DOI: 10.1186/s12882-021-02296-z. View

Horie R, Endo Y, Doi K . Estimated glomerular filtration rate may be an independent predictor for clinical outcomes regardless of acute kidney injury complication in the emergency department. PLoS One. 2021; 16(10):e0258665. PMC: 8516290. DOI: 10.1371/journal.pone.0258665. View

Dutta A, Hari K, Azizian J, Masmoudi Y, Khalid F, Kowal J . Incidence, Predictors, and Prognosis of Acute Kidney Injury Among Cardiac Arrest Survivors. J Intensive Care Med. 2020; 36(5):550-556. DOI: 10.1177/0885066620911353. View

Baek S, Kang J, Shin S, Park H, Kim M, Kim S . Predictive Factors of Duration of Continuous Renal Replacement Therapy in Acute Kidney Injury Survivors. Shock. 2019; 52(6):598-603. DOI: 10.1097/SHK.0000000000001328. View

Abou Elella R, Habib E, Mokrusova P, Joseph P, Aldalaty H, Al Ahmadi M . Incidence and outcome of acute kidney injury by the pRIFLE criteria for children receiving extracorporeal membrane oxygenation after heart surgery. Ann Saudi Med. 2017; 37(3):201-206. PMC: 6150581. DOI: 10.5144/0256-4947.2017.201. View

Jo J, Ryu S, Kim J, Lee E, Choi I . Comparison of five glomerular filtration rate estimating equations as predictors of acute kidney injury after cardiovascular surgery. Sci Rep. 2019; 9(1):11072. PMC: 6667489. DOI: 10.1038/s41598-019-47559-w. View

Ostermann M, Hall A, Crichton S . Low mean perfusion pressure is a risk factor for progression of acute kidney injury in critically ill patients - A retrospective analysis. BMC Nephrol. 2017; 18(1):151. PMC: 5415805. DOI: 10.1186/s12882-017-0568-8. View

10.

Razo-Vazquez A, Thornton K . Extracorporeal Membrane Oxygenation-What the Nephrologist Needs to Know. Adv Chronic Kidney Dis. 2016; 23(3):146-51. DOI: 10.1053/j.ackd.2016.02.004. View

11.

Coelho F, Watanabe M, Fonseca C, Padilha K, Vattimo M . Nursing Activities Score and Acute Kidney Injury. Rev Bras Enferm. 2017; 70(3):475-480. DOI: 10.1590/0034-7167-2016-0266. View

12.

Vinclair C, de Montmollin E, Sonneville R, Reuter J, Lebut J, Cally R . Factors associated with major adverse kidney events in patients who underwent veno-arterial extracorporeal membrane oxygenation. Ann Intensive Care. 2020; 10(1):44. PMC: 7167383. DOI: 10.1186/s13613-020-00656-w. View

13.

Chaves R, Rabello Filho R, Timenetsky K, Moreira F, Vilanova L, Bravim B . Extracorporeal membrane oxygenation: a literature review. Rev Bras Ter Intensiva. 2019; 31(3):410-424. PMC: 7005959. DOI: 10.5935/0103-507X.20190063. View

14.

Hoste E, Bagshaw S, Bellomo R, Cely C, Colman R, Cruz D . Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study. Intensive Care Med. 2015; 41(8):1411-23. DOI: 10.1007/s00134-015-3934-7. View

15.

Suer E, Akpinar C, Izol V, Bayazit Y, Sozen S, Cetin S . Predicting factors of acute kidney injury after partial nephrectomy and its impact on long-term renal function: A multicentre study of the Turkish Urooncology Association. Int J Clin Pract. 2021; 75(11):e14751. DOI: 10.1111/ijcp.14751. View

16.

Sun L, Wijeysundera D, Tait G, Beattie W . Association of intraoperative hypotension with acute kidney injury after elective noncardiac surgery. Anesthesiology. 2015; 123(3):515-23. DOI: 10.1097/ALN.0000000000000765. View

17.

Khwaja A . KDIGO clinical practice guidelines for acute kidney injury. Nephron Clin Pract. 2012; 120(4):c179-84. DOI: 10.1159/000339789. View

18.

Lucchini A, Elli S, De Felippis C, Greco C, Mulas A, Ricucci P . The evaluation of nursing workload within an Italian ECMO Centre: A retrospective observational study. Intensive Crit Care Nurs. 2019; 55:102749. DOI: 10.1016/j.iccn.2019.07.008. View

19.

Delmas C, Zapetskaia T, Conil J, Georges B, Vardon-Bounes F, Seguin T . 3-month prognostic impact of severe acute renal failure under veno-venous ECMO support: Importance of time of onset. J Crit Care. 2017; 44:63-71. DOI: 10.1016/j.jcrc.2017.10.022. View

20.

Ariyarathna D, Bhonsle A, Nim J, Huang C, Wong G, Sim N . Intraoperative vasopressor use and early postoperative acute kidney injury in elderly patients undergoing elective noncardiac surgery. Ren Fail. 2022; 44(1):648-659. PMC: 9009951. DOI: 10.1080/0886022X.2022.2061997. View