» Articles » PMID: 37060045

Cryptogenic Stroke As a Working Diagnosis: the Need for an Early and Comprehensive Diagnostic Work-up

Overview
Journal BMC Neurol
Publisher Biomed Central
Specialty Neurology
Date 2023 Apr 14
PMID 37060045
Authors
Affiliations
Soon will be listed here.
Abstract

In the Nordic Atrial Fibrillation and Stroke (NOR-FIB) study, the causes of ischemic stroke were identified in 43% of cryptogenic stroke patients monitored with implantable cardiac monitor (ICM), but one-third of these patients had non-cardioembolic causes. These results suggest the need for an early and comprehensive diagnostic work-up before inserting an ICM.

Citing Articles

Diagnostic Utility of N-Terminal Pro-B-Type Natriuretic Peptide in Identifying Atrial Fibrillation Post-Cryptogenic Stroke: A Systematic Review and Meta-Analysis.

Patel J, Bhaskar S Pathophysiology. 2024; 31(3):331-349.

PMID: 39051222 PMC: 11270372. DOI: 10.3390/pathophysiology31030024.

References
1.
Sakai Y, Lehman V, Eisenmenger L, Obusez E, Kharal G, Xiao J . Vessel wall MR imaging of aortic arch, cervical carotid and intracranial arteries in patients with embolic stroke of undetermined source: A narrative review. Front Neurol. 2022; 13:968390. PMC: 9366886. DOI: 10.3389/fneur.2022.968390. View

2.
Shen M, Arora R, Jalife J . Atrial Myopathy. JACC Basic Transl Sci. 2019; 4(5):640-654. PMC: 6872845. DOI: 10.1016/j.jacbts.2019.05.005. View

3.
Ratajczak-Tretel B, Lambert A, Al-Ani R, Arntzen K, Bakkejord G, Bekkeseth H . Underlying causes of cryptogenic stroke and TIA in the nordic atrial fibrillation and stroke (NOR-FIB) study - the importance of comprehensive clinical evaluation. BMC Neurol. 2023; 23(1):115. PMC: 10028765. DOI: 10.1186/s12883-023-03155-0. View

4.
Freilinger T, Schindler A, Schmidt C, Grimm J, Cyran C, Schwarz F . Prevalence of nonstenosing, complicated atherosclerotic plaques in cryptogenic stroke. JACC Cardiovasc Imaging. 2012; 5(4):397-405. DOI: 10.1016/j.jcmg.2012.01.012. View

5.
Zhao S, Ziegler P, Crawford M, Kwong C, Koehler J, Passman R . Evaluation of a clinical score for predicting atrial fibrillation in cryptogenic stroke patients with insertable cardiac monitors: results from the CRYSTAL AF study. Ther Adv Neurol Disord. 2019; 12:1756286419842698. PMC: 6460885. DOI: 10.1177/1756286419842698. View