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The Mediterranean Lifestyle to Contrast Low-Grade Inflammation Behavior in Cancer

Overview
Journal Nutrients
Date 2023 Apr 13
PMID 37049508
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Abstract

A healthy diet and an active lifestyle are both effective ways to prevent, manage, and treat many diseases, including cancer. A healthy, well-balanced diet not only ensures that the body gets the right amount of nutrients to meet its needs, but it also lets the body get substances that protect against and/or prevent certain diseases. It is now clear that obesity is linked to long-term diseases such as heart disease, diabetes, and cancer. The main reasons for people being overweight or obese are having bad eating habits and not moving around enough. Maintaining weight in the normal range may be one of the best things to avoid cancer. It has been scientifically proven that those who perform regular physical activity are less likely to develop cancer than those who lead a sedentary lifestyle. Moving regularly not only helps to maintain a normal body weight, avoiding the effects that favor tumor growth in overweight subjects, but also makes the immune system more resistant by counteracting the growth of tumor cells. Physical activity also helps prevent cardiovascular and metabolic diseases. In this review, it is highlighted that the association between the Mediterranean diet and physical activity triggers biological mechanisms capable of counteracting the low-grade chronic inflammation found in patients with cancer. This assumes that healthy lifestyles associated with cancer therapies can improve the expectations and quality of life of cancer patients.

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References
1.
Hong J, Park J . Systematic Review: Recommendations of Levels of Physical Activity among Colorectal Cancer Patients (2010-2019). Int J Environ Res Public Health. 2021; 18(6). PMC: 7999512. DOI: 10.3390/ijerph18062896. View

2.
Koelman L, Rodrigues C, Aleksandrova K . Effects of Dietary Patterns on Biomarkers of Inflammation and Immune Responses: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Adv Nutr. 2021; 13(1):101-115. PMC: 8803482. DOI: 10.1093/advances/nmab086. View

3.
Garcia-Chico C, Lopez-Ortiz S, Penin-Grandes S, Pinto-Fraga J, Valenzuela P, Emanuele E . Physical Exercise and the Hallmarks of Breast Cancer: A Narrative Review. Cancers (Basel). 2023; 15(1). PMC: 9818971. DOI: 10.3390/cancers15010324. View

4.
Key T, Bradbury K, Perez-Cornago A, Sinha R, Tsilidis K, Tsugane S . Diet, nutrition, and cancer risk: what do we know and what is the way forward?. BMJ. 2020; 368:m511. PMC: 7190379. DOI: 10.1136/bmj.m511. View

5.
Salvadori G, Mirisola M, Longo V . Intermittent and Periodic Fasting, Hormones, and Cancer Prevention. Cancers (Basel). 2021; 13(18). PMC: 8472354. DOI: 10.3390/cancers13184587. View