Polymer Nanomaterials for Use As Adjuvant Surgical Tools

Overview

Journal Wiley Interdiscip Rev Nanomed Nanobiotechnol

Specialty Biotechnology

Date 2023 Apr 12

PMID 37044114

Authors

Metecan Erdi

Anthony Sandler

Peter Kofinas

Affiliations

Soon will be listed here.

Abstract

Materials employed in the treatment of conditions encountered in surgical and clinical practice frequently face barriers in translation to application. Shortcomings can be generalized through their reduced mechanical stability, difficulty in handling, and inability to conform or adhere to complex tissue surfaces. To overcome an amalgam of challenges, research has sought the utilization of polymer-derived nanomaterials deposited in various fashions and formulations to improve the application and outcomes of surgical and clinical interventions. Clinically prevalent applications include topical wound dressings, tissue adhesives, surgical sealants, hemostats, and adhesion barriers, all of which have displayed the potential to act as superior alternatives to current materials used in surgical procedures. In this review, emphasis will be placed not only on applications, but also on various design strategies employed in fabrication. This review is designed to provide a broad and thought-provoking understanding of nanomaterials as adjuvant tools for the assisted treatment of pathologies prevalent in surgery. This article is categorized under: Implantable Materials and Surgical Technologies > Nanomaterials and Implants Implantable Materials and Surgical Technologies > Nanoscale Tools and Techniques in Surgery.

Citing Articles

Techniques for navigating postsurgical adhesions: Insights into mechanisms and future directions.

Chen J, Tang X, Wang Z, Perez A, Yao B, Huang K Bioeng Transl Med. 2023; 8(6):e10565.

PMID: 38023705 PMC: 10658569. DOI: 10.1002/btm2.10565.

Polydopamine-Coated Polycaprolactone Electrospun Nanofiber Membrane Loaded with Thrombin for Wound Hemostasis.

Cui D, Li M, Zhang P, Rao F, Huang W, Wang C Polymers (Basel). 2023; 15(14).

PMID: 37514511 PMC: 10385294. DOI: 10.3390/polym15143122.

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