[Multimodal Treatment of Localized High-grade Soft Tissue Sarcomas of the Extremities : Summary and Discussion of the Current S3 Guidelines on Adult Soft Tissue Sarcomas and the ESMO Guidelines on Soft Tissue and Visceral Sarcomas]

Overview

Journal Chirurgie (Heidelb)

Specialty General Surgery

Date 2023 Apr 11

PMID 37041391

Authors

Nikolas Schopow

Peter Hohenberger

Ines Gockel

Georg Osterhoff

Affiliations

Soon will be listed here.

Abstract

Soft tissue sarcomas are rare, heterogeneous tumors that are frequently in the extremities. Treatment includes surgical resection, combination chemotherapy and/or radiotherapy, as well as supplementary procedures such as isolated limb perfusion and regional deep hyperthermia. The prognosis depends on the tumor stage and the approximately 70 histological subtypes, with specific treatment approaches existing only for some subtypes. This review summarizes the recommendations of the German S3 guideline "Adult Soft Tissue Sarcomas" and the European Society for Medical Oncology (ESMO) guideline "Soft tissue and visceral sarcomas" regarding the diagnostic workup and therapy of soft tissue sarcomas of the extremities.

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