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Alcohol Use, HIV Stigma and Quality of Life Among Alcohol Consuming Men Living with HIV in India: A Mediation Analysis

Overview
Journal AIDS Behav
Date 2023 Apr 8
PMID 37031311
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Abstract

This study examined the hypothesis that HIV-related stigma mediates the effect of alcohol use on health-related quality of life (HRQoL) among alcohol consuming Indian men living with HIV (PLWH). The study used baseline data from a randomized controlled clinical trial entitled 'Alcohol and ART adherence: Assessment, Intervention, and Modeling in India. Participants completed surveys assessing demographic characteristics, alcohol use, HIV-related stigma, HRQoL. Mediation analysis was conducted to establish the mediation effect of HIV-related stigma on the relationship between alcohol use and HRQoL. The final mediation model showed that the effect of alcohol use on HRQoL were partially mediated by overall HIV-related stigma. Specially, 27.1% of the effects of alcohol use on HRQoL was mediated through overall HIV stigma. In the HIV stigma subdomain analyses, negative self-image mediated 14% and concerns with public attitudes (anticipated stigma) mediated 17.3% of the effect of alcohol use on HRQoL respectively. The findings suggest that efforts to reduce the negative impact of alcohol use on HRQoL and improve HRQoL among PLWH should include interventions addressing both alcohol use and specific forms of HIV-related stigma.

References
1.
Duko B, Ayalew M, Ayano G . The prevalence of alcohol use disorders among people living with HIV/AIDS: a systematic review and meta-analysis. Subst Abuse Treat Prev Policy. 2019; 14(1):52. PMC: 6854786. DOI: 10.1186/s13011-019-0240-3. View

2.
Balasubramani K, Paulson W, Chellappan S, Ramachandran R, Behera S, Balabaskaran Nina P . Epidemiology, Hot Spots, and Sociodemographic Risk Factors of Alcohol Consumption in Indian Men and Women: Analysis of National Family Health Survey-4 (2015-16), a Nationally Representative Cross-Sectional Study. Front Public Health. 2021; 9:617311. PMC: 8429933. DOI: 10.3389/fpubh.2021.617311. View

3.
Schensul S, Ha T, Schensul J, Vaz M, Singh R, Burleson J . The Role of Alcohol on Antiretroviral Therapy Adherence Among Persons Living With HIV in Urban India. J Stud Alcohol Drugs. 2017; 78(5):716-724. PMC: 5675422. DOI: 10.15288/jsad.2017.78.716. View

4.
Samet J, Phillips S, Horton N, Traphagen E, Freedberg K . Detecting alcohol problems in HIV-infected patients: use of the CAGE questionnaire. AIDS Res Hum Retroviruses. 2004; 20(2):151-5. DOI: 10.1089/088922204773004860. View

5.
Probst C, Parry C, Wittchen H, Rehm J . The socioeconomic profile of alcohol-attributable mortality in South Africa: a modelling study. BMC Med. 2018; 16(1):97. PMC: 6016129. DOI: 10.1186/s12916-018-1080-0. View