Current Trends in Graft Choice for Primary Anterior Cruciate Ligament Reconstruction - Part II: In-vivo Kinematics, Patient Reported Outcomes, Re-rupture Rates, Strength Recovery, Return to Sports and Complications
Overview
Authors
Affiliations
Postoperative patient satisfaction after anterior cruciate ligament reconstruction (ACL-R) is influenced mainly by the degree of pain, the need for reoperation, and functional performance in daily activities and sports. Graft choice has shown to have an influence on postoperative outcomes after ACL-R. While patient reported outcomes measurements do not differ between graft options, evidence shows that normal knee kinematics is not fully restored after ACL-R with an increase in postoperative anterior tibial translation (ATT). Postoperative graft rupture rates seem to favor bone-patella-tendon-bone (BPTB) and quadriceps tendon (QT) autografts over HT or allografts. While return to sports rates seem comparable between different graft types, postoperative extensor strength is reduced in patients with BPTB and QT whereas flexion strength is weakened in patients with HT. Postoperative donor site morbidity is highest in BPTB but comparable between HT and QT. With all graft options having advantages and drawbacks, graft choice must be individualized and chosen in accordance with the patient.
Lucidi G, Agostinone P, Di Paolo S, Dal Fabbro G, Serra M, Viotto M Orthop J Sports Med. 2025; 13(1):23259671241302348.
PMID: 39886263 PMC: 11780662. DOI: 10.1177/23259671241302348.
Ostojic M, Indelli P, Lovrekovic B, Volcarenghi J, Juric D, Hakam H Medicina (Kaunas). 2025; 60(12.
PMID: 39768969 PMC: 11678177. DOI: 10.3390/medicina60122090.
Petit C, Hussain Z, McPherson A, Petushek E, Montalvo A, White M Orthop J Sports Med. 2024; 12(11):23259671241289140.
PMID: 39583150 PMC: 11585031. DOI: 10.1177/23259671241289140.
Biocooperative Regenerative Materials by Harnessing Blood-Clotting and Peptide Self-Assembly.
Padilla-Lopategui S, Ligorio C, Bu W, Yin C, Laurenza D, Redondo C Adv Mater. 2024; 36(52):e2407156.
PMID: 39543808 PMC: 11681309. DOI: 10.1002/adma.202407156.
Patil B, Goyal S, Salwan A, Singh R Cureus. 2024; 16(9):e70333.
PMID: 39469369 PMC: 11513215. DOI: 10.7759/cureus.70333.