Nephron Sparing Surgery for a Patient with a Complicated Solitary Functioning Kidney and a Giant PT3 Renal Cell Carcinoma: A Case Report

Overview

Journal Front Surg

Specialty General Surgery

Date 2023 Apr 3

PMID 37009598

Authors

Minghao Yu

Jiatong Zhou

Xun Shangguan

Subo Qian

Jie Ding

Jun Qi

Affiliations

Soon will be listed here.

Abstract

A solitary functioning kidney (SFK) with renal cell carcinoma (RCC) is an imperative indication for nephron-sparing surgery (NSS). Nevertheless, a giant pT3 RCC mass (maximum diameter >20 cm) on the functioning side of a patient with SFK is extremely rare. However, whether NSS is more beneficial than radical nephrectomy (RN) in such patients is controversial. Here, we present the case of a 71-year-old female patient with a 20 cm*16 cm RCC mass in the SFK, who initially presented with hematuria and acute urinary tract obstructive anuria caused by renal calculi. The patient underwent NSS treatment after our evaluation, and the 26-month follow-up revealed that her renal function recovered to the state before the tumor formation. In addition, no relapse or metastasis was detected.

References

Becker F, Roos F, Janssen M, Brenner W, Hampel C, Siemer S . Short-term functional and oncologic outcomes of nephron-sparing surgery for renal tumours ≥ 7 cm. Eur Urol. 2011; 59(6):931-7. DOI: 10.1016/j.eururo.2011.02.017. View

Karellas M, OBrien M, Jang T, Bernstein M, Russo P . Partial nephrectomy for selected renal cortical tumours of ≥ 7 cm. BJU Int. 2010; 106(10):1484-7. PMC: 4319322. DOI: 10.1111/j.1464-410X.2010.09405.x. View

Ljungberg B, Albiges L, Abu-Ghanem Y, Bedke J, Capitanio U, Dabestani S . European Association of Urology Guidelines on Renal Cell Carcinoma: The 2022 Update. Eur Urol. 2022; 82(4):399-410. DOI: 10.1016/j.eururo.2022.03.006. View

Bindayi A, Hamilton Z, Mcdonald M, Yim K, Millard F, McKay R . Neoadjuvant therapy for localized and locally advanced renal cell carcinoma. Urol Oncol. 2017; 36(1):31-37. DOI: 10.1016/j.urolonc.2017.07.015. View

Berdjis N, Hakenberg O, Novotny V, Manseck A, Oehlschlager S, Wirth M . Nephron-sparing surgery for renal cell carcinoma in the solitary kidney. Scand J Urol Nephrol. 2007; 41(1):10-3. DOI: 10.1080/00365590600911225. View