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Advances in Single-Photon Emission Computed Tomography: Hardware, Software, and Myocardial Flow Reserve

Overview
Journal Cardiol Clin
Publisher Elsevier
Date 2023 Apr 1
PMID 37003670
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Abstract

The clinical presentation of coronary artery disease (CAD) has changed during the last 20 years with less ischemia on stress testing and more nonobstructive CAD on coronary angiography. Single-photon emission computed tomography (SPECT) myocardial perfusion imaging should include the measurement of myocardial flow reserve and assessment of coronary calcium for the diagnosis of nonobstructive CAD and coronary microvascular disease. SPECT/CT systems provide reliable attenuation correction for better specificity and low-dose CT for coronary calcium evaluation. SPECT MFR measurement is accurate, well validated, and repeatable.

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