Correlation Between Morphological Characteristics of Macular Edema and Visual Acuity in Young Patients with Idiopathic Intermediate Uveitis

Overview

Journal Medicina (Kaunas)

Publisher MDPI

Specialty General Medicine

Date 2023 Mar 29

PMID 36984530

Authors

Ludovico Iannetti

Fabio Scarinci

Ludovico Alisi

Marta Armentano

Lorenzo Sampalmieri

Maurizio La Cava

Magda Gharbiya

Affiliations

Soon will be listed here.

Abstract

Macular edema (ME) is a common complication of intermediate uveitis (IU). It is often responsible for a decrease in visual acuity (VA). Three distinct patterns of macular edema have been described in intermediate uveitis, namely, cystoid macular edema (CME), diffuse macular edema (DME), and serous retinal detachment (SRD). The current study aims to describe the characteristics of macular edema in young patients with idiopathic intermediate uveitis and to correlate its features with VA using spectral domain optical coherence tomography (SD-OCT). A total of 27 eyes from 18 patients with idiopathic IU complicated by ME were included in this retrospective study. All patients underwent SD-OCT; data were gathered at the onset of ME. Best-corrected VA (BCVA) was correlated with the morphological features of ME. BCVA was negatively correlated with Ellipsoid Zone (EZ) disruption ( = 0.00021), cystoid pattern ( = 0.00021), central subfield thickness (CST) ( < 0.001), and serous retinal detachment (0.037). In ME secondary to idiopathic IU, VA negatively correlates with Ellipsoid Zone disruption and increases in CST. Moreover, vision is influenced by the presence of cysts in the inner nuclear and outer nuclear layers and by the neuroepithelium detachment.

Citing Articles

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PMID: 37893595 PMC: 10608233. DOI: 10.3390/medicina59101877.

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