Oncologists' Knowledge, Practice and Attitude Toward Fertility Preservation: A National Survey

Overview

Journal Life (Basel)

Specialty Biology

Date 2023 Mar 29

PMID 36983955

Authors

Ahmed Al Ghaithi

Eyas Al Rashdi

Maryam Al Shukri

Rahma Al Ghabshi

Halima Albalushi

Affiliations

Soon will be listed here.

Abstract

Background: Improved chemotherapy and radiotherapy treatment protocols, fortunately, increased the rates of cancer survivors over the years. However, these treatments may result in infertility or subfertility. Oncologists are considered the gateway for knowledge about cancer and its treatments' effects. Several studies showed that many oncologists do not discuss fertility preservation with their patients. This study aimed to explore the perspective of oncologists in Oman on fertility preservation.

Methods: A cross-sectional study of physicians and surgeons dealing with patients with cancer was conducted from June 2021 to December 2021. A standardized and validated questionnaire was used to collect data.

Results: Participants reported that they are knowledgeable about sperm cryopreservation and gonadotropin-releasing hormone agonists use but not other methods of fertility preservation. About 94% of the participants reported that they need more knowledge about fertility preservation. More than half of the participants had never encountered cancer patients who used ovarian cryopreservation, testicular tissue cryopreservation, in vitro fertilization with embryo cryopreservation and oocyte cryopreservation. The majority (78%) agreed that discussing fertility preservation with newly diagnosed cancer patients is a high priority.

Conclusions: Oncologists in Oman are supportive of fertility preservation. The lack of knowledge and unavailability of well-structured fertility preservation services in Oman hinders the initiation of fertility preservation discussions.

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References

Chung J, Lao T, Li T . Evaluation of the awareness of, attitude to, and knowledge about fertility preservation in cancer patients among clinical practitioners in Hong Kong. Hong Kong Med J. 2017; 23(6):556-61. DOI: 10.12809/hkmj176840. View

Zhang H, Wang G, Jiang B, Cao M, Jiang Q, Yin L . The Knowledge, Attitude, and Self-Reported Behaviors of Oncology Physicians Regarding Fertility Preservation in Adult Cancer Patients. J Cancer Educ. 2019; 35(6):1119-1127. PMC: 7679324. DOI: 10.1007/s13187-019-01567-6. View

Tholeti P, Uppangala S, Bhat V, Udupa K, Kumar V, Patted S . Oncofertility: Knowledge, Attitudes, and Barriers Among Indian Oncologists and Gynecologists. J Adolesc Young Adult Oncol. 2020; 10(1):71-77. DOI: 10.1089/jayao.2020.0034. View

Griggs J, Sorbero M, Mallinger J, Quinn M, Waterman M, Brooks B . Vitality, mental health, and satisfaction with information after breast cancer. Patient Educ Couns. 2006; 66(1):58-66. DOI: 10.1016/j.pec.2006.10.008. View

Rabah D, Wahdan I, Merdawy A, Abourafe B, Arafa M . Oncologists' knowledge and practice towards sperm cryopreservation in Arabic communities. J Cancer Surviv. 2010; 4(3):279-83. DOI: 10.1007/s11764-010-0140-z. View

Schover L, Brey K, Lichtin A, Lipshultz L, Jeha S . Knowledge and experience regarding cancer, infertility, and sperm banking in younger male survivors. J Clin Oncol. 2002; 20(7):1880-9. DOI: 10.1200/JCO.2002.07.175. View

Green D, Liu W, Kutteh W, Ke R, Shelton K, Sklar C . Cumulative alkylating agent exposure and semen parameters in adult survivors of childhood cancer: a report from the St Jude Lifetime Cohort Study. Lancet Oncol. 2014; 15(11):1215-23. PMC: 4192599. DOI: 10.1016/S1470-2045(14)70408-5. View

Dow K . Having children after breast cancer. Cancer Pract. 1994; 2(6):407-13. View

Revel A, Revel-Vilk S . Pediatric fertility preservation: is it time to offer testicular tissue cryopreservation?. Mol Cell Endocrinol. 2008; 282(1-2):143-9. DOI: 10.1016/j.mce.2007.11.003. View

10.

Adams E, Hill E, Watson E . Fertility preservation in cancer survivors: a national survey of oncologists' current knowledge, practice and attitudes. Br J Cancer. 2013; 108(8):1602-15. PMC: 3668471. DOI: 10.1038/bjc.2013.139. View

11.

Quinn G, Vadaparampil S, Lee J, Jacobsen P, Bepler G, Lancaster J . Physician referral for fertility preservation in oncology patients: a national study of practice behaviors. J Clin Oncol. 2009; 27(35):5952-7. DOI: 10.1200/JCO.2009.23.0250. View

12.

Blumenfeld Z . Fertility Preservation Using GnRH Agonists: Rationale, Possible Mechanisms, and Explanation of Controversy. Clin Med Insights Reprod Health. 2019; 13:1179558119870163. PMC: 6710670. DOI: 10.1177/1179558119870163. View

13.

Shimizu C, Bando H, Kato T, Mizota Y, Yamamoto S, Fujiwara Y . Physicians' knowledge, attitude, and behavior regarding fertility issues for young breast cancer patients: a national survey for breast care specialists. Breast Cancer. 2012; 20(3):230-40. DOI: 10.1007/s12282-011-0328-8. View

14.

King L, Quinn G, Vadaparampil S, Gwede C, Miree C, Wilson C . Oncology nurses' perceptions of barriers to discussion of fertility preservation with patients with cancer. Clin J Oncol Nurs. 2008; 12(3):467-76. DOI: 10.1188/08.CJON.467-476. View

15.

Rozati H, Handley T, Jayasena C . Process and Pitfalls of Sperm Cryopreservation. J Clin Med. 2017; 6(9). PMC: 5615282. DOI: 10.3390/jcm6090089. View

16.

Green D, Kawashima T, Stovall M, Leisenring W, Sklar C, Mertens A . Fertility of male survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2009; 28(2):332-9. PMC: 2815721. DOI: 10.1200/JCO.2009.24.9037. View

17.

Mor V, Malin M, Allen S . Age differences in the psychosocial problems encountered by breast cancer patients. J Natl Cancer Inst Monogr. 1994; (16):191-7. View

18.

Dyer K, Quinn G . Cancer and fertility preservation in Puerto Rico: a qualitative study of healthcare provider perceptions. Support Care Cancer. 2016; 24(8):3353-60. PMC: 5044868. DOI: 10.1007/s00520-016-3166-6. View

19.

Lambertini M, Del Mastro L, Pescio M, Andersen C, Azim Jr H, Peccatori F . Cancer and fertility preservation: international recommendations from an expert meeting. BMC Med. 2016; 14:1. PMC: 4700580. DOI: 10.1186/s12916-015-0545-7. View

20.

Newton H, Friend A, Feltbower R, Hayden C, Picton H, Glaser A . Survival from cancer in young people: An overview of late effects focusing on reproductive health. Acta Obstet Gynecol Scand. 2019; 98(5):573-582. DOI: 10.1111/aogs.13584. View