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Functionally Significant Variants in Genes Associated with Abdominal Obesity: A Review

Overview
Journal J Pers Med
Date 2023 Mar 29
PMID 36983642
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Abstract

The high prevalence of obesity and of its associated diseases is a major problem worldwide. Genetic predisposition and the influence of environmental factors contribute to the development of obesity. Changes in the structure and functional activity of genes encoding adipocytokines are involved in the predisposition to weight gain and obesity. In this review, variants in genes associated with adipocyte function are examined, as are variants in genes associated with metabolic aberrations and the accompanying disorders in visceral obesity.

Citing Articles

Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity.

Bairqdar A, Shakhtshneider E, Ivanoshchuk D, Mikhailova S, Kashtanova E, Shramko V J Pers Med. 2023; 13(10).

PMID: 37888112 PMC: 10608506. DOI: 10.3390/jpm13101500.

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