The Associations Between Insomnia Severity and Health Outcomes in the United States

Overview

Journal J Clin Med

Specialty General Medicine

Date 2023 Mar 29

PMID 36983438

Authors

Francois-Xavier Chalet

Paul Saskin

Ajay Ahuja

Jeffrey Thompson

Abisola Olopoenia

Kushal Modi

Charles M Morin

Emerson M Wickwire

Affiliations

Soon will be listed here.

Abstract

Little is known about the associations between insomnia severity, insomnia symptoms, and key health outcomes. Using 2020 United States National Health and Wellness Survey (NHWS) data, we conducted a retrospective, cross-sectional analysis to determine the associations between insomnia severity and a number of health outcomes germane to patients (health-related quality of life (HRQoL), employers and government (workplace productivity), and healthcare payers (healthcare resource utilization (HCRU)). The Insomnia Severity Index (ISI) questionnaire was used to evaluate overall insomnia severity. HRQoL was assessed using the physical and mental component summary scores of the Short Form-36v2 (SF-36v2) questionnaire, and health utility status was measured using the Short Form-6D (SF-6D) and EuroQoL-5D (EQ-5D) questionnaires. Workplace productivity was measured using the Work Productivity and Activity Impairment (WPAI) questionnaire. After adjusting for confounders, greater insomnia severity was significantly associated with worsened quality of life, decreased productivity, and increased HCRU in an apparent linear fashion. These findings have important implications for future research, including the need for specific assessment of insomnia symptoms and their impact on key health outcomes.

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References

Walters S, Brazier J . Comparison of the minimally important difference for two health state utility measures: EQ-5D and SF-6D. Qual Life Res. 2005; 14(6):1523-32. DOI: 10.1007/s11136-004-7713-0. View

Frendl D, Ware Jr J . Patient-reported functional health and well-being outcomes with drug therapy: a systematic review of randomized trials using the SF-36 health survey. Med Care. 2014; 52(5):439-45. DOI: 10.1097/MLR.000000000000010311. View

Gupta S, Goren A, Phillips A, Stewart M . Self-reported burden among caregivers of patients with multiple sclerosis. Int J MS Care. 2014; 14(4):179-87. PMC: 3882984. DOI: 10.7224/1537-2073-14.4.179. View

Wickwire E . Value-Based Sleep in the Workplace. Sleep. 2016; 39(10):1767-1768. PMC: 5020358. DOI: 10.5665/sleep.6150. View

Ford D, Kamerow D . Epidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention?. JAMA. 1989; 262(11):1479-84. DOI: 10.1001/jama.262.11.1479. View

Reilly M, Zbrozek A, Dukes E . The validity and reproducibility of a work productivity and activity impairment instrument. Pharmacoeconomics. 1993; 4(5):353-65. DOI: 10.2165/00019053-199304050-00006. View

Sarsour K, Kalsekar A, Swindle R, Foley K, Walsh J . The association between insomnia severity and healthcare and productivity costs in a health plan sample. Sleep. 2011; 34(4):443-50. PMC: 3065254. DOI: 10.1093/sleep/34.4.443. View

Kessler R, Berglund P, Coulouvrat C, Hajak G, Roth T, Shahly V . Insomnia and the performance of US workers: results from the America insomnia survey. Sleep. 2011; 34(9):1161-71. PMC: 3157657. DOI: 10.5665/SLEEP.1230. View

DiBonaventura M, Gupta S, McDonald M, Sadosky A . Evaluating the health and economic impact of osteoarthritis pain in the workforce: results from the National Health and Wellness Survey. BMC Musculoskelet Disord. 2011; 12:83. PMC: 3110556. DOI: 10.1186/1471-2474-12-83. View

10.

Grima N, Bei B, Mansfield D . Insomnia theory and assessment. Aust J Gen Pract. 2019; 48(4):193-197. DOI: 10.31128/AJGP-12-18-4780. View

11.

Morin C, Belleville G, Belanger L, Ivers H . The Insomnia Severity Index: psychometric indicators to detect insomnia cases and evaluate treatment response. Sleep. 2011; 34(5):601-8. PMC: 3079939. DOI: 10.1093/sleep/34.5.601. View

12.

Herdman M, Gudex C, Lloyd A, Janssen M, Kind P, Parkin D . Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L). Qual Life Res. 2011; 20(10):1727-36. PMC: 3220807. DOI: 10.1007/s11136-011-9903-x. View

13.

Morin C, Stone J, Trinkle D, Mercer J, Remsberg S . Dysfunctional beliefs and attitudes about sleep among older adults with and without insomnia complaints. Psychol Aging. 1993; 8(3):463-7. DOI: 10.1037//0882-7974.8.3.463. View

14.

Wickwire E, Shaya F, Scharf S . Health economics of insomnia treatments: The return on investment for a good night's sleep. Sleep Med Rev. 2016; 30:72-82. DOI: 10.1016/j.smrv.2015.11.004. View

15.

Goren A, Liu X, Gupta S, Simon T, Phatak H . Quality of life, activity impairment, and healthcare resource utilization associated with atrial fibrillation in the US National Health and Wellness Survey. PLoS One. 2013; 8(8):e71264. PMC: 3741145. DOI: 10.1371/journal.pone.0071264. View

16.

Thorndike F, Ritterband L, Saylor D, Magee J, Gonder-Frederick L, Morin C . Validation of the insomnia severity index as a web-based measure. Behav Sleep Med. 2011; 9(4):216-23. DOI: 10.1080/15402002.2011.606766. View

17.

DiBonaventura M, Richard L, Kumar M, Forsythe A, Flores N, Moline M . The Association between Insomnia and Insomnia Treatment Side Effects on Health Status, Work Productivity, and Healthcare Resource Use. PLoS One. 2015; 10(10):e0137117. PMC: 4591007. DOI: 10.1371/journal.pone.0137117. View

18.

Riemann D, Baglioni C, Bassetti C, Bjorvatn B, Groselj L, Ellis J . European guideline for the diagnosis and treatment of insomnia. J Sleep Res. 2017; 26(6):675-700. DOI: 10.1111/jsr.12594. View

19.

Montazeri A, Vahdaninia M, Mousavi S, Asadi-Lari M, Omidvari S, Tavousi M . The 12-item medical outcomes study short form health survey version 2.0 (SF-12v2): a population-based validation study from Tehran, Iran. Health Qual Life Outcomes. 2011; 9:12. PMC: 3063185. DOI: 10.1186/1477-7525-9-12. View

20.

Daley M, Morin C, LeBlanc M, Gregoire J, Savard J . The economic burden of insomnia: direct and indirect costs for individuals with insomnia syndrome, insomnia symptoms, and good sleepers. Sleep. 2009; 32(1):55-64. PMC: 2625324. View