Choline Supplements: An Update

Overview

Journal Front Endocrinol (Lausanne)

Specialty Endocrinology

Date 2023 Mar 23

PMID 36950691

Authors

Urna Kansakar

Valentina Trimarco

Pasquale Mone

Fahimeh Varzideh

Angela Lombardi

Gaetano Santulli

Affiliations

Soon will be listed here.

Abstract

In this comprehensive review, we examine the main preclinical and clinical investigations assessing the effects of different forms of choline supplementation currently available, including choline alfoscerate (CHNOP), also known as alpha-glycerophosphocholine (α-GPC, or GPC), choline bitartrate, lecithin, and citicoline, which are cholinergic compounds and precursors of acetylcholine. Extensively used as food supplements, they have been shown to represent an effective strategy for boosting memory and enhancing cognitive function.

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