Memory Retrieval, Reconsolidation, and Extinction: Exploring the Boundary Conditions of Post-conditioning Cue Exposure

Overview

Journal Front Synaptic Neurosci

Date 2023 Mar 20

PMID 36937567

Authors

Nicole C Ferrara

Janine L Kwapis

Sydney Trask

Affiliations

Soon will be listed here.

Abstract

Following fear conditioning, behavior can be reduced by giving many CS-alone presentations in a process known as extinction or by presenting a few CS-alone presentations and interfering with subsequent memory reconsolidation. While the two share procedural similarities, both the behavioral outcomes and the neurobiological underpinnings are distinct. Here we review the neural and behavioral mechanisms that produce these separate behavioral reductions, as well as some factors that determine whether or not a retrieval-dependent reconsolidation process or an extinction process will be in effect.

Citing Articles

Elevated fear states facilitate ventral hippocampal engagement of basolateral amygdala neuronal activity.

Ritger A, Parker R, Trask S, Ferrara N Front Behav Neurosci. 2024; 18:1347525.

PMID: 38420349 PMC: 10899678. DOI: 10.3389/fnbeh.2024.1347525.

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