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Tingible Body Macrophages: Gargantuan Chameleons of the Germinal Center

Overview
Journal J Exp Med
Specialties Allergy & Immunology
General Medicine
Date 2023 Mar 14
PMID 36917028
Authors
Elisa Madeleine Baudon
Marc Bajenoff
Affiliations
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Abstract

Tingible body macrophages in lymph node are involved in cleaning up debris from apoptotic B cells. Gurwisz et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20222173) and Grootveld et al. (2023. Cell.https://doi.org/10.1016/j.cell.2023.02.004) report how tingible body macrophages, originating from tissue-resident macrophages, clear apoptotic B cells in the germinal center using a "stand-hunting" strategy.

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