On the Recovery of the Electroretinogram After Removal of Intravitreal Zinc Particles

Overview

Journal Doc Ophthalmol

Specialty Ophthalmology

Date 1987 Apr 1

PMID 3691295

Citations 1

Authors

J G Schmidt

C Nies

R Mansfeld-Nies

Affiliations

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Abstract

The influence of intravitreal zinc particles (1.3 mm2) in the eyes of rats caused the amplitudes of the electroretinogram to decrease to about 50% of the initial values within 24 hours, whereas the prolongation of the peak times began only on the third day after particle implantation. The removal of the zinc particles after 30 days led to only partial recovery of the amplitudes, whereas the peak times reached normal values. Dissociated behaviour of the amplitudes and peak times as described here was not found in earlier experiments with intravitreal iron, copper or lead particles of the same size. The extraction of intravitreal zinc particles (1.3 mm2) one day after implantation resulted in a recovery of the amplitudes up to 85%.

Citing Articles

On the recovery of the electroretinogram of rats after removal of intravitreal lead particles.

Schmidt J, Ehring E Doc Ophthalmol. 1986; 62(2):181-90.

PMID: 3956368 DOI: 10.1007/BF00229129.

References

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