» Articles » PMID: 36908501

Prevalence of Pain and Use of Prescription Opioids Among Older Adults: Results from the Brazilian Longitudinal Study of Aging (ELSI-Brazil)

Overview
Date 2023 Mar 13
PMID 36908501
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Pain has a significant impact on people's quality of life. The use of prescription opioids to treat pain is associated with an increased risk of opioid use disorders and overdose death. We measured the prevalence of recurrent pain, prescription opioid use, and associations between chronic conditions and prescription opioid use among Brazilian older adults.

Methods: We used data from the first population-based longitudinal study of aging in Brazil (ELSI-Brazil), 2019-2020 (mean age = 63.3; 54.4% female). Outcomes were: (1) experience of recurrent pain and (2) use of opioid analgesics in the past three months among those who experience pain. Exposures included selected health conditions, history of falls, and hospitalizations.

Findings: Prevalence of pain (n = 9234) was 36.9% (95% CI: 32.6-41.1). Pain was reported more frequently by female participants, low-income individuals, and those with a previous diagnosis of arthritis, chronic back pain, depressive symptoms, history of falls, and hospitalizations. Prevalence of opioid use among those reporting pain (n = 3350) was 30% (95% CI: 23.1-38.0). Prevalence of opioid use was higher among female and single individuals. In adjusted models, arthritis, chronic back pain, and presence of depressive symptoms were associated with prescription opioid use.

Interpretation: Prescription opioid use was reported by a sizable portion of the older adults who suffer from pain in Brazil. In a context of growing consumption of prescription opioids, opioid misuse has the potential to increase in the future. Surveillance of prescription opioid use is critical to prevent their harmful consequences.

Funding: ELSI-Brazil was funded by the Brazilian Ministry of Health.

Citing Articles

Observational evidence linking psychotropic medicines to the dispensing of opioid agents in later life.

Almeida O, Page A, Sanfilippo F, Preen D, Etherton-Beer C Psychogeriatrics. 2024; 24(3):665-674.

PMID: 38561326 PMC: 11578014. DOI: 10.1111/psyg.13123.


Conditioned morphine tolerance promotes neurogenesis, dendritic remodelling and pro-plasticity molecules in the adult rat hippocampus.

Nejad G, Mottarlini F, Tavassoli Z, Caffino L, Fumagalli F, Homberg J Addict Biol. 2024; 29(3):e13377.

PMID: 38506630 PMC: 11061850. DOI: 10.1111/adb.13377.


Shift in hospital opioid use during the COVID-19 pandemic in Brazil: a time-series analysis of one million prescriptions.

Carvalho R, de Magalhaes-Barbosa M, Bianchi L, Rodrigues-Santos G, da Cunha A, Bastos F Sci Rep. 2023; 13(1):17197.

PMID: 37821638 PMC: 10567754. DOI: 10.1038/s41598-023-44533-5.


Pain in older adults with dementia: improving diagnosis to provide better care.

Caramelli P Arq Neuropsiquiatr. 2023; 81(8):705-706.

PMID: 37647903 PMC: 10468231. DOI: 10.1055/s-0043-1772671.

References
1.
van den Beuken-van Everdingen M, Hochstenbach L, Joosten E, Tjan-Heijnen V, Janssen D . Update on Prevalence of Pain in Patients With Cancer: Systematic Review and Meta-Analysis. J Pain Symptom Manage. 2016; 51(6):1070-1090.e9. DOI: 10.1016/j.jpainsymman.2015.12.340. View

2.
Tsang A, Von Korff M, Lee S, Alonso J, Karam E, Angermeyer M . Common chronic pain conditions in developed and developing countries: gender and age differences and comorbidity with depression-anxiety disorders. J Pain. 2008; 9(10):883-91. DOI: 10.1016/j.jpain.2008.05.005. View

3.
Atzeni F, Alciati A, Bazzichi L, Govoni M, Biasi G, Di Franco M . Sociodemographic factors in fibromyalgia: results from the Italian Fibromyalgia Registry. Clin Exp Rheumatol. 2022; 40(6):1183-1188. DOI: 10.55563/clinexprheumatol/64963d. View

4.
Cross M, Smith E, Hoy D, Carmona L, Wolfe F, Vos T . The global burden of rheumatoid arthritis: estimates from the global burden of disease 2010 study. Ann Rheum Dis. 2014; 73(7):1316-22. DOI: 10.1136/annrheumdis-2013-204627. View

5.
Macinko J, Mullachery P . Education-related health inequities in noncommunicable diseases: an analysis of the Brazilian National Health Survey, 2013 and 2019. Cad Saude Publica. 2022; 38Suppl 1(Suppl 1):e00137721. DOI: 10.1590/0102-311X00137721. View