Mesotocin and Vasotocin in the Brain of the Lizard Gekko Gecko. An Immunocytochemical Study

Overview

Journal Cell Tissue Res

Specialties Anatomy & Histology
Cell Biology

Date 1987 Dec 1

PMID 3690641

Citations 14

Authors

T Thepen

P Voorn

C J Stoll

A A Sluiter

C W Pool

A H Lohman

Affiliations

Soon will be listed here.

Abstract

The distribution of mesotocin and vasotocin was studied in the brain of the lizard Gekko gecko with antisera specific for either peptide. Both mesotocinergic and vasotocinergic perikarya are found in the paraventricular and supraoptic nuclei of the hypothalamus, whereas vasotocinergic neurons are exclusively present in the bed nucleus of the stria terminalis and in a cell group of the rhombencephalon. The distributional pattern of the mesotocinergic fibers corresponds closely to that of the vasotocinergic fibers. However, throughout the entire brain the mesotocinergic innervation is less dense than the vasotocinergic innervation. No sex differences are present in the mesotocinergic fiber system.

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References

Goossens N, Blahser S, Oksche A, VANDESANDE F, Dierickx K . Immunocytochemical investigation of the hypothalamo-neurohypophysial system in birds. Cell Tissue Res. 1977; 184(1):1-13. DOI: 10.1007/BF00220523. View

Troiano R, Siegel A . The ascending and descending connections of the hypothalamus in the cat. Exp Neurol. 1975; 49(1 Pt 1):161-73. DOI: 10.1016/0014-4886(75)90202-2. View

Goossens N, Dierickx K, VANDESANDE F . Immunocytochemical localization of vasotocin and mesotocin in the hypothalamus of lacertilian reptiles. Cell Tissue Res. 1979; 200(2):223-7. DOI: 10.1007/BF00236415. View

Ananthanarayanan V . Nature and distribution of neurosecretory cells of the reptilian brain. Z Zellforsch Mikrosk Anat. 1955; 43(1):8-16. DOI: 10.1007/BF00319746. View

Pool C, Madlener S, Diegenbach P, Sluiter A, van der Sluis P . Quantification of antiserum reactivity in immunocytochemistry. Two new methods for measuring peroxidase activity on antigen-coupled beads incubated according to an immunocytoperoxidase method. J Histochem Cytochem. 1984; 32(9):921-8. DOI: 10.1177/32.9.6205048. View

Stoll C, Voorn P . The distribution of hypothalamic and extrahypothalamic vasotocinergic cells and fibers in the brain of a lizard, Gekko gecko: presence of a sex difference. J Comp Neurol. 1985; 239(2):193-204. DOI: 10.1002/cne.902390206. View

de Vries G, Buijs R . The origin of the vasopressinergic and oxytocinergic innervation of the rat brain with special reference to the lateral septum. Brain Res. 1983; 273(2):307-17. DOI: 10.1016/0006-8993(83)90855-7. View

VANDESANDE F, Dierickx K . Immunocytochemical demonstration of separate vasotocinergic and mesotocinergic neurons in the amphibian hypothalamic magnocellular neurosecretory system. Cell Tissue Res. 1976; 175(3):289-96. DOI: 10.1007/BF00218707. View

Conrad L, Pfaff D . Efferents from medial basal forebrain and hypothalamus in the rat. II. An autoradiographic study of the anterior hypothalamus. J Comp Neurol. 1976; 169(2):221-61. DOI: 10.1002/cne.901690206. View

10.

Gesell M, Callard I . The hypothalamic-hypophysial neurosecretory system in the iguanid lizard, Dipsosaurus dorsalis: a qualitative and quantitative study. Gen Comp Endocrinol. 1972; 19(3):397-404. DOI: 10.1016/0016-6480(72)90238-9. View

11.

Van den Dungen H, Buijs R, Pool C, Terlou M . The distribution of vasotocin and isotocin in the brain of the rainbow trout. J Comp Neurol. 1982; 212(2):146-57. DOI: 10.1002/cne.902120205. View

12.

Dogterom J, Snijdewint F, Buijs R . The distribution of vasopressin and oxytocin in the rat brain. Neurosci Lett. 2009; 9(4):341-6. DOI: 10.1016/0304-3940(78)90206-9. View

13.

Goossens N, Dierickx K, VANDESANDE F . Immunocytochemical localization of vasotocin and isotocin in the preopticohypophysial neurosecretory system of teleosts. Gen Comp Endocrinol. 1977; 32(4):371-5. DOI: 10.1016/0016-6480(77)90216-7. View

14.

Smeets W, Hoogland P, Lohman A . A forebrain atlas of the lizard Gekko gecko. J Comp Neurol. 1986; 254(1):1-19. DOI: 10.1002/cne.902540102. View

15.

Buijs R . Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat. Pathways to the limbic system, medulla oblongata and spinal cord. Cell Tissue Res. 1978; 192(3):423-35. DOI: 10.1007/BF00212323. View

16.

Buijs R, Swaab D, Dogterom J, van Leeuwen F . Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat. Cell Tissue Res. 1978; 186(3):423-33. DOI: 10.1007/BF00224932. View

17.

DeVries G, Buijs R, van Leeuwen F, Caffe A, Swaab D . The vasopressinergic innervation of the brain in normal and castrated rats. J Comp Neurol. 1985; 233(2):236-54. DOI: 10.1002/cne.902330206. View