Advances in Neurodegenerative Diseases

Overview

Journal J Clin Med

Specialty General Medicine

Date 2023 Mar 11

PMID 36902495

Authors

Jeroen Van Schependom

Miguel DHaeseleer

Affiliations

Soon will be listed here.

Abstract

Neurological disorders are the leading cause of physical and cognitive disability across the globe, currently affecting approximately 15% of the worldwide population [...].

Citing Articles

Viruses and the Brain-A Relationship Prone to Trouble.

Mielcarska M, Rouse B Viruses. 2025; 17(2).

PMID: 40006958 PMC: 11860391. DOI: 10.3390/v17020203.

The Spastic Paraplegia-Centers of Excellence Research Network (SP-CERN): Clinical Trial Readiness for Hereditary Spastic Paraplegia.

Schierbaum L, Quiroz V, Yang K, Rong J, Battaglia N, Zubair U Neurol Genet. 2025; 11(2):e200249.

PMID: 39996129 PMC: 11849523. DOI: 10.1212/NXG.0000000000200249.

Animal models in biomedical research: Relevance of .

Obafemi O, Ayeleso A, Adewale O, Unuofin J, Ekundayo B, Ntwasa M Heliyon. 2025; 11(1):e41605.

PMID: 39850441 PMC: 11754520. DOI: 10.1016/j.heliyon.2024.e41605.

Neprilysin-Mediated Amyloid Beta Clearance and Its Therapeutic Implications in Neurodegenerative Disorders.

Saxena S, Ansari S, Maurya V, Kumar S, Sharma D, Malhotra H ACS Pharmacol Transl Sci. 2024; 7(12):3645-3657.

PMID: 39698259 PMC: 11651204. DOI: 10.1021/acsptsci.4c00400.

Designed Cell-Penetrating Peptide Constructs for Inhibition of Pathogenic Protein Self-Assembly.

Kalmouni M, Oh Y, Alata W, Magzoub M Pharmaceutics. 2024; 16(11).

PMID: 39598566 PMC: 11597747. DOI: 10.3390/pharmaceutics16111443.

References

Plow M, Motl R, Finlayson M, Bethoux F . Response heterogeneity in a randomized controlled trial of telerehabilitation interventions among adults with multiple sclerosis. J Telemed Telecare. 2020; 28(9):642-652. DOI: 10.1177/1357633X20964693. View

Lebrun C, Blanc F, Brassat D, Zephir H, De Seze J . Cognitive function in radiologically isolated syndrome. Mult Scler. 2010; 16(8):919-25. DOI: 10.1177/1352458510375707. View

Welch H, Walsh J, Larson E . The cost of institutional care in Alzheimer's disease: nursing home and hospital use in a prospective cohort. J Am Geriatr Soc. 1992; 40(3):221-4. DOI: 10.1111/j.1532-5415.1992.tb02072.x. View

Bacmeister C, Barr H, McClain C, Thornton M, Nettles D, Welle C . Motor learning promotes remyelination via new and surviving oligodendrocytes. Nat Neurosci. 2020; 23(7):819-831. PMC: 7329620. DOI: 10.1038/s41593-020-0637-3. View

Peruzzi A, Zarbo I, Cereatti A, Croce U, Mirelman A . An innovative training program based on virtual reality and treadmill: effects on gait of persons with multiple sclerosis. Disabil Rehabil. 2016; 39(15):1557-1563. DOI: 10.1080/09638288.2016.1224935. View

Kappos L, Wolinsky J, Giovannoni G, Arnold D, Wang Q, Bernasconi C . Contribution of Relapse-Independent Progression vs Relapse-Associated Worsening to Overall Confirmed Disability Accumulation in Typical Relapsing Multiple Sclerosis in a Pooled Analysis of 2 Randomized Clinical Trials. JAMA Neurol. 2020; 77(9):1132-1140. PMC: 7281382. DOI: 10.1001/jamaneurol.2020.1568. View

Genchi A, Brambilla E, Sangalli F, Radaelli M, Bacigaluppi M, Furlan R . Neural stem cell transplantation in patients with progressive multiple sclerosis: an open-label, phase 1 study. Nat Med. 2023; 29(1):75-85. PMC: 9873560. DOI: 10.1038/s41591-022-02097-3. View

Dalgas U, Langeskov-Christensen M, Stenager E, Riemenschneider M, Hvid L . Exercise as Medicine in Multiple Sclerosis-Time for a Paradigm Shift: Preventive, Symptomatic, and Disease-Modifying Aspects and Perspectives. Curr Neurol Neurosci Rep. 2019; 19(11):88. DOI: 10.1007/s11910-019-1002-3. View

McNamara N, Munro D, Bestard-Cuche N, Uyeda A, Bogie J, Hoffmann A . Microglia regulate central nervous system myelin growth and integrity. Nature. 2022; 613(7942):120-129. PMC: 9812791. DOI: 10.1038/s41586-022-05534-y. View

10.

Preziosa P, Pagani E, Meani A, Moiola L, Rodegher M, Filippi M . Slowly Expanding Lesions Predict 9-Year Multiple Sclerosis Disease Progression. Neurol Neuroimmunol Neuroinflamm. 2022; 9(2). PMC: 8808355. DOI: 10.1212/NXI.0000000000001139. View

11.

Faissner S, Plemel J, Gold R, Yong V . Progressive multiple sclerosis: from pathophysiology to therapeutic strategies. Nat Rev Drug Discov. 2019; 18(12):905-922. DOI: 10.1038/s41573-019-0035-2. View

12.

Denissen S, Nagels G . Artificial intelligence will change MS care within the next 10 years: Yes. Mult Scler. 2022; 28(14):2171-2173. DOI: 10.1177/13524585221130421. View

13.

Schulz D, Kopp B, Kunkel A, Faiss J . Cognition in the early stage of multiple sclerosis. J Neurol. 2006; 253(8):1002-10. DOI: 10.1007/s00415-006-0145-8. View

14.

Cencioni M, Mattoscio M, Magliozzi R, Bar-Or A, Muraro P . B cells in multiple sclerosis - from targeted depletion to immune reconstitution therapies. Nat Rev Neurol. 2021; 17(7):399-414. DOI: 10.1038/s41582-021-00498-5. View

15.

Portaccio E, Bellinvia A, Fonderico M, Pasto L, Razzolini L, Totaro R . Progression is independent of relapse activity in early multiple sclerosis: a real-life cohort study. Brain. 2022; 145(8):2796-2805. DOI: 10.1093/brain/awac111. View

16.

Sosnoff J, Wajda D, Sandroff B, Roeing K, Sung J, Motl R . Dual task training in persons with Multiple Sclerosis: a feasability randomized controlled trial. Clin Rehabil. 2017; 31(10):1322-1331. DOI: 10.1177/0269215517698028. View

17.

Hauser S, Cree B . Treatment of Multiple Sclerosis: A Review. Am J Med. 2020; 133(12):1380-1390.e2. PMC: 7704606. DOI: 10.1016/j.amjmed.2020.05.049. View

18.

Kadel R, Evans-Lacko S, Tramarin A, Stopazzolo G . Cost-Effectiveness of Tele-Video-Consultation for the Neuro-Surgical Emergency Management at the General Hospitals in Italy. Front Neurosci. 2018; 12:908. PMC: 6288303. DOI: 10.3389/fnins.2018.00908. View

19.

Rojas J, Patrucco L, Miguez J, Besada C, Cristiano E . Brain atrophy in radiologically isolated syndromes. J Neuroimaging. 2014; 25(1):68-71. DOI: 10.1111/jon.12182. View

20.

Ivanova J, Birnbaum H, Samuels S, Davis M, Phillips A, Meletiche D . The cost of disability and medically related absenteeism among employees with multiple sclerosis in the US. Pharmacoeconomics. 2009; 27(8):681-91. DOI: 10.2165/11314700-000000000-00000. View