Validation of the COVID-19-12O Score for Predicting Readmissions/revisits in Patients with SARS-CoV-2 Pneumonia Discharged from the Emergency Department

Overview

Journal Rev Clin Esp (Barc)

Specialty General Medicine

Date 2023 Mar 4

PMID 36870418

Authors

B Espinosa

N Ruso

J M Ramos-Rincon

O Moreno-Perez

P Llorens

Affiliations

Soon will be listed here.

Abstract

Objective: The COVID-19-12O-score has been validated to determine the risk of respiratory failure in patients hospitalized for COVID-19. Our study aims to assess whether the score is effective in patients with SARS-CoV-2 pneumonia discharged from a hospital emergency department (HED) to predict readmission and revisit.

Method: Retrospective cohort of patients with SARS-CoV-2 pneumonia discharged consecutively from an HUS of a tertiary hospital, from January 7 to February 17, 2021, where we applied the COVID-19-12O -score, with a cut-off point of 9 points to define the risk of admission or revisit. The primary outcome variable was revisit with or without hospital readmission after 30 days of discharge from HUS.

Results: We included 77 patients, with a median age of 59 years, 63.6% men and Charlson index of 2. 9.1% had an emergency room revisit and 15.3% had a deferred hospital admission. The relative risk (RR) for emergency journal was 0.46 (0.04-4.62, 95% CI, p=0.452), and the RR for hospital readmission was 6.88 (1.20-39.49, 95% CI, p<0.005).

Conclusions: The COVID-19-12O -score is effective in determining the risk of hospital readmission in patients discharged from HED with SARS-CoV-2 pneumonia, but is not useful for assessing the risk of revisit.

References

Wiersinga W, Rhodes A, Cheng A, Peacock S, Prescott H . Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review. JAMA. 2020; 324(8):782-793. DOI: 10.1001/jama.2020.12839. View

Albert A, Jacob J, Malchair P, Llopis F, Fuentes L, Martin C . Predictors of revisits within 1 year by patients after acute COVID-19: the HUBCOVID365 cohort study. Emergencias. 2022; 34(1):38-46. View

Berenguer J, Borobia A, Ryan P, Rodriguez-Bano J, Bellon J, Jarrin I . Development and validation of a prediction model for 30-day mortality in hospitalised patients with COVID-19: the COVID-19 SEIMC score. Thorax. 2021; 76(9):920-929. PMC: 7908055. DOI: 10.1136/thoraxjnl-2020-216001. View

Ramos-Martinez A, Parra-Ramirez L, Morras I, Carnevali M, Jimenez-Ibanez L, Rubio-Rivas M . Frequency, risk factors, and outcomes of hospital readmissions of COVID-19 patients. Sci Rep. 2021; 11(1):13733. PMC: 8253752. DOI: 10.1038/s41598-021-93076-0. View

Garcia-Martinez A, Lopez-Barbeito B, Coll-Vinent B, Placer A, Font C, Vargas C . Mortality in patients treated for COVID-19 in the emergency department of a tertiary care hospital during the first phase of the pandemic: Derivation of a risk model for emergency departments. Emergencias. 2021; 33(4):273-281. View

Gutierrez Gabriel S, Dominguez Garcia M, Perez Manas G, Moreno Garcia N, Silvan Dominguez M, Andres E . Biological markers and follow-up after discharge home of patients with COVID-19 pneumonia. Emergencias. 2021; 33(3):174-180. View

Wynants L, Van Calster B, Collins G, Riley R, Heinze G, Schuit E . Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal. BMJ. 2020; 369:m1328. PMC: 7222643. DOI: 10.1136/bmj.m1328. View

Ena J, Segura-Heras J, Fonseca-Aizpuru E, Lopez-Reboiro M, Gracia-Gutierrez A, Martin-Oterino J . Derivation and validation of a risk score for admission to the Intensive Care Unit in patients with COVID-19. Rev Clin Esp (Barc). 2021; 222(1):1-12. PMC: 8437856. DOI: 10.1016/j.rceng.2021.06.001. View

Artero A, Madrazo M, Fernandez-Garces M, Muino Miguez A, Garcia A, Crestelo Vieitez A . Severity Scores in COVID-19 Pneumonia: a Multicenter, Retrospective, Cohort Study. J Gen Intern Med. 2021; 36(5):1338-1345. PMC: 7878165. DOI: 10.1007/s11606-021-06626-7. View

10.

Lalueza A, Lora-Tamayo J, Maestro-de la Calle G, Folgueira D, Arrieta E, de Miguel-Campo B . A predictive score at admission for respiratory failure among hospitalized patients with confirmed 2019 Coronavirus Disease: a simple tool for a complex problem. Intern Emerg Med. 2021; 17(2):515-524. PMC: 8082224. DOI: 10.1007/s11739-021-02748-2. View

11.

Casas-Rojo J, Anton-Santos J, Millan-Nunez-Cortes J, Lumbreras-Bermejo C, Ramos-Rincon J, Roy-Vallejo E . Clinical characteristics of patients hospitalized with COVID-19 in Spain: Results from the SEMI-COVID-19 Registry. Rev Clin Esp (Barc). 2020; 220(8):480-494. PMC: 7480740. DOI: 10.1016/j.rce.2020.07.003. View

12.

Moreno-Perez O, Ribes I, Fuertes-Kenneally L, Carratala J, Roman F, Otero-Rodriguez S . Effective fast-track ambulatory care pathway for patients with COVID-19 at risk for poor outcome: the COVID-A2R model in a hospital emergency department. Emergencias. 2022; 34(2):103-110. View

13.

Fresco L, Osorio G, Carbo M, Marco D, Garcia-Gozalbes J, Artajona L . Risk score for mortality due to COVID-19: a prospective temporal validation cohort study in the emergency department of a tertiary care hospital. Emergencias. 2022; 34(3):196-203. View

14.

Lalueza A, Lora-Tamayo J, de la Calle C, Sayas-Catalan J, Arrieta E, Maestro G . [The early use of sepsis scores to predict respiratory failure and mortality in non-ICU patients with COVID-19]. Rev Clin Esp. 2020; 222(5):293-298. PMC: 7648653. DOI: 10.1016/j.rce.2020.10.004. View

15.

Rubio-Rivas M, Corbella X, Formiga F, Menendez Fernandez E, Martin Escalante M, Banos Fernandez I . Risk Categories in COVID-19 Based on Degrees of Inflammation: Data on More Than 17,000 Patients from the Spanish SEMI-COVID-19 Registry. J Clin Med. 2021; 10(10). PMC: 8161115. DOI: 10.3390/jcm10102214. View

16.

Eiros J, Lopez-Izquierdo R, Bouza E . Coronaviruses that are always present. Emergencias. 2020; 32(3):160-161. View

17.

Lopez-Ayala P, Alcaraz-Serna A, Valls Carbo A, Cuadrado Cenzual M, Torrejon Martinez M, Picado A . Procalcitonin concentration in the emergency department predicts 30-day mortality in COVID-19 better than the lymphocyte count, the neutrophil-tolymphocyte ratio, or the C-reactive protein level. Emergencias. 2022; 34(2):119-127. View