What is Cancer Metabolism?

Overview

Journal Cell

Publisher Cell Press

Specialty Cell Biology

Date 2023 Mar 1

PMID 36858045

Authors

Lydia W S Finley

Affiliations

Soon will be listed here.

Abstract

The uptake and metabolism of nutrients support fundamental cellular process from bioenergetics to biomass production and cell fate regulation. While many studies of cell metabolism focus on cancer cells, the principles of metabolism elucidated in cancer cells apply to a wide range of mammalian cells. The goal of this review is to discuss how the field of cancer metabolism provides a framework for revealing principles of cell metabolism and for dissecting the metabolic networks that allow cells to meet their specific demands. Understanding context-specific metabolic preferences and liabilities will unlock new approaches to target cancer cells to improve patient care.

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