» Articles » PMID: 36848535

Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder: Prevention in the Context of New Trauma

Overview
Specialty General Medicine
Date 2023 Feb 27
PMID 36848535
Authors
Affiliations
Soon will be listed here.
Abstract

Posttraumatic stress disorder (PTSD) is a disabling psychiatric disorder that can result from experiencing a traumatic event. While a single index trauma can result in PTSD, patients often have additional traumatic events over the course of their lives. Despite this, little research to date has focused on prevention of PTSD recurrence following a novel traumatic experience. We present three cases of individuals with chronic PTSD who experienced an additional traumatic experience during treatment with transcranial magnetic stimulation (TMS) at VA Providence. Despite expectations to the contrary, TMS appeared to prevent a recurrence or worsening of their PTSD symptoms. We discuss possible neurobiological explanations for these outcomes and implications for possible use of TMS to prevent PTSD following trauma.

References
1.
OReardon J, Solvason H, Janicak P, Sampson S, Isenberg K, Nahas Z . Efficacy and safety of transcranial magnetic stimulation in the acute treatment of major depression: a multisite randomized controlled trial. Biol Psychiatry. 2007; 62(11):1208-16. DOI: 10.1016/j.biopsych.2007.01.018. View

2.
Dedert E, Green K, Calhoun P, Yoash-Gantz R, Taber K, Mumford M . Association of trauma exposure with psychiatric morbidity in military veterans who have served since September 11, 2001. J Psychiatr Res. 2009; 43(9):830-6. PMC: 2754834. DOI: 10.1016/j.jpsychires.2009.01.004. View

3.
Clancy C, Graybeal A, Tompson W, Badgett K, Feldman M, Calhoun P . Lifetime trauma exposure in veterans with military-related posttraumatic stress disorder: association with current symptomatology. J Clin Psychiatry. 2006; 67(9):1346-53. DOI: 10.4088/jcp.v67n0904. View

4.
Blevins C, Weathers F, Davis M, Witte T, Domino J . The Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5): Development and Initial Psychometric Evaluation. J Trauma Stress. 2015; 28(6):489-98. DOI: 10.1002/jts.22059. View

5.
Pitman R, Sanders K, Zusman R, Healy A, Cheema F, Lasko N . Pilot study of secondary prevention of posttraumatic stress disorder with propranolol. Biol Psychiatry. 2002; 51(2):189-92. DOI: 10.1016/s0006-3223(01)01279-3. View