Esophageal and Head and Neck Cancer Patients Attending Ocean Road Cancer Institute in Tanzania from 2019 to 2021: An Observational Study

Overview

Journal Int J Environ Res Public Health

Publisher MDPI

Specialties Environmental Health
Public Health

Date 2023 Feb 25

PMID 36833998

Authors

Luco P Mwelange

Simon H D Mamuya

Julius Mwaiselage

Magne Bratveit

Bente E Moen

Affiliations

Soon will be listed here.

Abstract

Background: Cancer in Africa is an emerging public health problem that needs urgent preventive measures, particularly in workplaces where exposure to carcinogens may occur. In Tanzania, the incidence rate of cancer and mortality rates due to cancers are increasing, with approximately 50,000 new cases each year. This is estimated to double by 2030.

Methods: Our hospital-based cross-sectional study describes the characteristics of newly diagnosed patients with head and neck or esophageal cancer from the Ocean Road Cancer Institute (ORCI), Tanzania. We used an ORCI electronic system to extract secondary data for these patients.

Results: According to the cancer registration, there were 611 head and neck and 975 esophageal cancers recorded in 2019-2021. Two-thirds of these cancer patients were male. About 25% of the cancer patients used tobacco and alcohol, and over 50% were involved in agriculture.

Conclusion: Descriptions of 1586 head and neck cancer patients and esophageal cancer patients enrolled in a cancer hospital in Tanzania are given. The information may be important for designing future studies of these cancers and may be of value in the development of cancer prevention measures.

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References

Miranda-Galvis M, Loveless R, Kowalski L, Teng Y . Impacts of Environmental Factors on Head and Neck Cancer Pathogenesis and Progression. Cells. 2021; 10(2). PMC: 7917998. DOI: 10.3390/cells10020389. View

Togawa K, Leon M, Lebailly P, Beane Freeman L, Nordby K, Baldi I . Cancer incidence in agricultural workers: Findings from an international consortium of agricultural cohort studies (AGRICOH). Environ Int. 2021; 157:106825. PMC: 8484858. DOI: 10.1016/j.envint.2021.106825. View

Amizadeh M, Safari-Kamalabadi M, Askari-Saryazdi G, Amizadeh M, Reihani-Kermani H . Pesticide Exposure and Head and Neck Cancers: A Case-Control Study in an Agricultural Region. Iran J Otorhinolaryngol. 2017; 29(94):275-285. PMC: 5610376. View

Alaouna M, Hull R, Penny C, Dlamini Z . Esophageal cancer genetics in South Africa. Clin Exp Gastroenterol. 2019; 12:157-177. PMC: 6485038. DOI: 10.2147/CEG.S182000. View

Purdue M, Jarvholm B, Bergdahl I, Hayes R, Baris D . Occupational exposures and head and neck cancers among Swedish construction workers. Scand J Work Environ Health. 2006; 32(4):270-5. DOI: 10.5271/sjweh.1010. View

Patel K, Wakhisi J, Mining S, Mwangi A, Patel R . Esophageal Cancer, the Topmost Cancer at MTRH in the Rift Valley, Kenya, and Its Potential Risk Factors. ISRN Oncol. 2014; 2013:503249. PMC: 3893746. DOI: 10.1155/2013/503249. View

Kim J, Seo S, Kim Y, Kim D . Review of carcinogenicity of hexavalent chrome and proposal of revising approval standards for an occupational cancers in Korea. Ann Occup Environ Med. 2018; 30:7. PMC: 5791242. DOI: 10.1186/s40557-018-0215-2. View

Carton M, Barul C, Menvielle G, Cyr D, Sanchez M, Pilorget C . Occupational exposure to solvents and risk of head and neck cancer in women: a population-based case-control study in France. BMJ Open. 2017; 7(1):e012833. PMC: 5223686. DOI: 10.1136/bmjopen-2016-012833. View

Leonel A, Bonan R, Pinto M, Kowalski L, Perez D . The pesticides use and the risk for head and neck cancer: A review of case-control studies. Med Oral Patol Oral Cir Bucal. 2020; 26(1):e56-e63. PMC: 7806356. DOI: 10.4317/medoral.23962. View

10.

Argirion I, Zarins K, Defever K, Suwanrungruang K, Chang J, Pongnikorn D . Temporal Changes in Head and Neck Cancer Incidence in Thailand Suggest Changing Oropharyngeal Epidemiology in the Region. J Glob Oncol. 2019; 5:1-11. PMC: 6449079. DOI: 10.1200/JGO.18.00219. View

11.

Erinoso O, Okoturo E, Gbotolorun O, Effiom O, Awolola N, Soyemi S . Emerging Trends in the Epidemiological Pattern of Head and Neck Cancers in Lagos, Nigeria. Ann Med Health Sci Res. 2017; 6(5):301-307. PMC: 5414443. DOI: 10.4103/amhsr.amhsr_30_16. View

12.

Radoi L, Sylla F, Matrat M, Barul C, Menvielle G, Delafosse P . Head and neck cancer and occupational exposure to leather dust: results from the ICARE study, a French case-control study. Environ Health. 2019; 18(1):27. PMC: 6440008. DOI: 10.1186/s12940-019-0469-3. View

13.

Jethwa A, Khariwala S . Tobacco-related carcinogenesis in head and neck cancer. Cancer Metastasis Rev. 2017; 36(3):411-423. PMC: 5709040. DOI: 10.1007/s10555-017-9689-6. View

14.

Rebbeck T . Cancer in sub-Saharan Africa. Science. 2020; 367(6473):27-28. DOI: 10.1126/science.aay4743. View

15.

Pinkiewicz M, Dorobisz K, Zatonski T . Human Papillomavirus-Associated Head and Neck Cancers. Where are We Now? A Systematic Review. Cancer Manag Res. 2022; 14:3313-3324. PMC: 9709860. DOI: 10.2147/CMAR.S379173. View

16.

Huang S, Wu I, Wu D, Wu C, Yang J, Chen Y . Occupational risks of esophageal cancer in Taiwanese men. Kaohsiung J Med Sci. 2012; 28(12):654-9. DOI: 10.1016/j.kjms.2012.04.034. View

17.

Gasmelseed N, Abudris D, Elhaj A, Eltayeb E, Elmadani A, Elhassan M . Patterns of Esophageal Cancer in the National Cancer Institute at the University of Gezira, in Gezira State, Sudan, in 1999-2012. Asian Pac J Cancer Prev. 2015; 16(15):6481-90. DOI: 10.7314/apjcp.2015.16.15.6481. View

18.

Gressier A, Gourier G, Metges J, Dewitte J, Lodde B, Lucas D . Occupational Exposures and Esophageal Cancer: Prog Study. Int J Environ Res Public Health. 2022; 19(16). PMC: 9408612. DOI: 10.3390/ijerph19169782. View

19.

Domper Arnal M, Ferrandez Arenas A, Lanas Arbeloa A . Esophageal cancer: Risk factors, screening and endoscopic treatment in Western and Eastern countries. World J Gastroenterol. 2015; 21(26):7933-43. PMC: 4499337. DOI: 10.3748/wjg.v21.i26.7933. View

20.

Rai B, Bramhankar M . Tobacco use among Indian states: Key findings from the latest demographic health survey 2019-2020. Tob Prev Cessat. 2021; 7:19. PMC: 7942198. DOI: 10.18332/tpc/132466. View