» Articles » PMID: 36832252

Intracardiac Thrombi in Preterm Infants-A Case Study and Review of the Literature

Overview
Specialty Radiology
Date 2023 Feb 25
PMID 36832252
Authors
Affiliations
Soon will be listed here.
Abstract

Intracardiac thrombi in preterm infants are not common but may lead to fatal outcomes. Predisposing and risk factors include small vessel size, hemodynamic instability, immaturity of the fibrinolytic system, indwelling central catheters and sepsis. In this paper, we present our own experience with a case of a catheter-related right atrial thrombus in a preterm infant, which was successfully treated with an aspiration thrombectomy. Then, we review the literature on intracardiac thrombosis in preterm infants: epidemiology, pathophysiology, clinical signs, echocardiographic diagnostic features and treatment options are discussed.

Citing Articles

Right atrial thrombus in a neonate with Aspergillus colonization secondary to central venous catheter: a case report.

El-Shirbiny H, Ramadan M, Gomaa M Eur Heart J Case Rep. 2025; 9(2):ytaf049.

PMID: 39935817 PMC: 11811767. DOI: 10.1093/ehjcr/ytaf049.


Over-the-Wire Retrieval of Infectious Hemodialysis Catheter-Related Right Atrial Thrombus Causing Recurrent Pleural Empyema and Sepsis: A Case-Based Review.

Barilaro G, Galassi A, Gatto M, Ciocci G, Fabrizio F, Cappelli A J Clin Med. 2024; 13(22).

PMID: 39597776 PMC: 11594965. DOI: 10.3390/jcm13226630.

References
1.
Giuffre B, Compagnoni G, Farina C, Mosca F . Successful use of tissue plasminogen activator (t-PA) in catheter-related intracardiac thrombi of two premature infants. Acta Paediatr. 1998; 87(6):695-8. DOI: 10.1080/080352598750014148. View

2.
. The European Cooperative Study on the clinical significance of right heart thrombi. European Working Group on Echocardiography. Eur Heart J. 1989; 10(12):1046-59. DOI: 10.1093/oxfordjournals.eurheartj.a059427. View

3.
Kenet G, Barg A, Nowak-Gottl U . Hemostasis in the Very Young. Semin Thromb Hemost. 2018; 44(7):617-623. DOI: 10.1055/s-0038-1660852. View

4.
de Boode W, van der Lee R, Eriksen B, Nestaas E, Dempsey E, Singh Y . The role of Neonatologist Performed Echocardiography in the assessment and management of neonatal shock. Pediatr Res. 2018; 84(Suppl 1):57-67. PMC: 6257224. DOI: 10.1038/s41390-018-0081-1. View

5.
El-Segaier M, Khan M, Khan Z, Momenah T, Galal M . Recombinant Tissue Plasminogen Activator in the Treatment of Neonates with Intracardiac and Great Vessels Thrombosis. Pediatr Cardiol. 2015; 36(8):1582-7. DOI: 10.1007/s00246-015-1199-0. View