Diagnostic Workup of Childhood Interstitial Lung Disease

Overview

Journal Eur Respir Rev

Specialty Pulmonary Medicine

Date 2023 Feb 22

PMID 36813289

Authors

Nadia Nathan

Matthias Griese

Katarzyna Michel

Julia Carlens

Carlee Gilbert

Nagehan Emiralioglu

Alba Torrent-Vernetta

Honorata Marczak

Brigitte Willemse

Celine Delestrain

Ralph Epaud

Affiliations

Soon will be listed here.

Abstract

Childhood interstitial lung diseases (chILDs) are rare and heterogeneous diseases with significant morbidity and mortality. An accurate and quick aetiological diagnosis may contribute to better management and personalised treatment. On behalf of the European Respiratory Society Clinical Research Collaboration for chILD (ERS CRC chILD-EU), this review summarises the roles of the general paediatrician, paediatric pulmonologists and expert centres in the complex diagnostic workup. Each patient's aetiological chILD diagnosis must be reached without prolonged delays in a stepwise approach from medical history, signs, symptoms, clinical tests and imaging, to advanced genetic analysis and specialised procedures including bronchoalveolar lavage and biopsy, if necessary. Finally, as medical progress is fast, the need to revisit a diagnosis of "undefined chILD" is stressed.

Citing Articles

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