Postoperative Resting Metabolic Rate and Successful Weight Loss After Roux-en-Y Gastric Bypass

Overview

Journal Obes Surg

Date 2023 Feb 22

PMID 36808386

Authors

Lilian Cardia

Roberto de Cleva

Leandro Ferreira

Alexandre Vieira Gadducci

Priscila Estabile

Paulo Roberto Santos Silva

Julia Greve

Marco Aurelio Santo

Affiliations

Soon will be listed here.

Abstract

Objective: To analyze whether changes in RMR 6 months after RYGB could be a predictor of weight loss on late follow-up.

Methods: Prospective study of 45 individuals submitted to RYGB in a university tertiary care hospital. Body composition was evaluated by bioelectrical impedance analysis and RMR by indirect calorimetry before (T0), 6 (T1), and 36 months (T2) after surgery.

Results: RMR/day was lower in T1 (1.552 ± 275 kcal/day) than in T0 (1734 ± 372 kcal/day; p < 0.001) with a return to similar values at T2 (1.795 ± 396 kcal/day; p < 0.001). In T0, there was no correlation between RMR/kg and body composition. In T1, there was a negative correlation between RMR and BW, BMI, and % FM, and a positive correlation with % FFM. The results in T2 were similar to T1. There was a significant increase in RMR/kg between T0, T1, and T2 (13.6 ± 2.2 kcal/kg, 16.9 ± 2.7 kcal/kg, and 19.9 ± 3.4 kcal/kg) in the total group and according to gender. Eighty percent of the patients who had increased RMR/kg ≥ 2 kcal at T1 achieved > 50% EWL in T2, particularly in women (odds ratio: 27.09, p < 0.037).

Conclusions: The increase in RMR/kg after RYGB is a major factor related to a satisfactory % excess weight loss on late follow-up.

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