How to Manage Coagulopathies in Critically Ill Patients

Overview

Journal Intensive Care Med

Specialty Critical Care

Date 2023 Feb 22

PMID 36808215

Authors

Julie Helms

Toshiaki Iba

Jean Marie Connors

Satoshi Gando

Marcel Levi

Ferhat Meziani

Jerrold H Levy

Affiliations

Soon will be listed here.

Abstract

Coagulopathy is a severe and frequent complication in critically ill patients, for which the pathogenesis and presentation may be variable depending on the underlying disease. Based on the dominant clinical phenotype, the current review differentiates between hemorrhagic coagulopathies, characterized by a hypocoagulable and hyperfibrinolysis state, and thrombotic coagulopathies with a systemic prothrombotic and antifibrinolytic phenotype. We discuss the differences in pathogenesis and treatment of the common coagulopathies.

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