Proton Beam Therapy As a Curative Treatment for a Young Case of Unresectable Tracheal Adenoid Cystic Carcinoma

Overview

Journal Intern Med

Specialty General Medicine

Date 2023 Feb 15

PMID 36792199

Authors

Takashi Kinoshita

Hidenobu Ishii

Yuki Sakazaki

Koichi Azuma

Jun Sasaki

Takaaki Tokito

Masaki Tominaga

Etsuyo Ogou

Tomotaka Kawayama

Tomoaki Hoshino

Affiliations

Soon will be listed here.

Abstract

Primary tracheal adenoid cystic carcinoma (TACC) is a rare malignancy without an established treatment. Central airway obstruction due to TACC often decreases the quality of life and has life-threatening consequences. A 19-year-old man with unresectable TACC and central airway obstruction suffered from progressive cough and dyspnea after exercise. Proton beam therapy (PBT) was selected as the preferred treatment over systemic anti-cancer chemotherapy for TACC. PBT led to complete remission of TACC and the almost complete disappearance of the respiratory symptoms without adverse events. PBT is a useful and safe treatment for unresectable primary TACC.

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