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Acute Bacterial Encephalitis Complicated with Recurrent Nasopharyngeal Carcinoma Associated with Infection: A Case Report

Overview
Journal Front Neurol
Specialty Neurology
Date 2023 Feb 13
PMID 36776576
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Abstract

() is an extremely rare pathogenic bacterium, which causes serious infections in patients with primary immunodeficiency or tumors, and it is often misdiagnosed. has rarely been known to cause a neurologic infection. We describe the first case of acute bacterial encephalitis associated with infection in a man with recurrent nasopharyngeal carcinoma, which was successfully cured by antibiotics. The patient initially presented with recurrent episodes of fever and later showed impaired consciousness but these symptoms were alleviated with antibiotic therapy including cefoperazone/sulbactam. This study highlights that rapid and accurate pathogen detection metagenomic next-generation sequencing and early use of appropriate antibiotics can improve the prognosis of patients with suspected neurologic infection. Early treatment for underlying primary diseases can also significantly improve the outcomes of patients.

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