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Low Skeletal Muscle Index Adjusted for Body Mass Index Is an Independent Risk Factor for Inflammatory Bowel Disease Surgical Complications

Abstract

Background: This study aims to evaluate sarcopenia defined by skeletal muscle index (SMI) with cutoffs adjusted for sex and body mass index as a predictive marker for postoperative outcomes among individuals with inflammatory bowel disease.

Methods: The SMI was measured using the cross-sectional computed tomography images at the lumbar spine. Multivariate logistic regression was performed to identify independent risk factors of postoperative complications.

Results: Ninety-one patients were included in the study. In multivariate analysis, sarcopenia (odds ratio = 5.37; confidence interval: 1.04-27.6) was predictive of infectious postoperative complications.

Conclusions: Sarcopenia as defined by the SMI is a predictor for 30-day postoperative infection complications in inflammatory bowel disease surgeries.

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References
1.
Weijs P, Looijaard W, Dekker I, Stapel S, Girbes A, Oudemans-van Straaten H . Low skeletal muscle area is a risk factor for mortality in mechanically ventilated critically ill patients. Crit Care. 2014; 18(2):R12. PMC: 4028783. DOI: 10.1186/cc13189. View

2.
OBrien S, Kavanagh R, Carey B, Maher M, OConnor O, Andrews E . The impact of sarcopenia and myosteatosis on postoperative outcomes in patients with inflammatory bowel disease. Eur Radiol Exp. 2018; 2(1):37. PMC: 6246753. DOI: 10.1186/s41747-018-0072-3. View

3.
Cosnes J, Gower-Rousseau C, Seksik P, Cortot A . Epidemiology and natural history of inflammatory bowel diseases. Gastroenterology. 2011; 140(6):1785-94. DOI: 10.1053/j.gastro.2011.01.055. View

4.
Bamba S, Sasaki M, Takaoka A, Takahashi K, Imaeda H, Nishida A . Sarcopenia is a predictive factor for intestinal resection in admitted patients with Crohn's disease. PLoS One. 2017; 12(6):e0180036. PMC: 5482469. DOI: 10.1371/journal.pone.0180036. View

5.
Jinek T, Adamcik L, Vrba R, Duda M, Skrovina M . Risk factors and post-operative complications after gastrectomy for cancer. Rozhl Chir. 2018; 97(8):384-393. View