Blood Transcriptome Analysis Revealed the Crosstalk Between Severe COVID-19 and Systemic Lupus Erythematosus

Overview

Journal J Infect

Specialty Infectious Diseases

Date 2023 Feb 12

PMID 36775249

Authors

Ruogang Meng

Ning Zhang

Feixiang Yang

Zhihao Xu

Zhengyang Wu

Yinan Du

Affiliations

Soon will be listed here.

Citing Articles

Identification and experimental validation of diagnostic and prognostic genes CX3CR1, PID1 and PTGDS in sepsis and ARDS using bulk and single-cell transcriptomic analysis and machine learning.

Jiang J, Chen Y, Su Y, Zhang L, Qian H, Song X Front Immunol. 2025; 15:1480542.

PMID: 39763654 PMC: 11700820. DOI: 10.3389/fimmu.2024.1480542.

Non-causal association of COVID-19 with systemic lupus erythematosus: Evidence from a bidirectional Mendelian randomization.

Yang F, Zhang N, Meng R, Wang K, Liu T, Meng J J Infect. 2023; 86(4):e87-e90.

PMID: 36822407 PMC: 9941312. DOI: 10.1016/j.jinf.2023.02.028.

References

Hornung V, Hartmann R, Ablasser A, Hopfner K . OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids. Nat Rev Immunol. 2014; 14(8):521-8. PMC: 7097587. DOI: 10.1038/nri3719. View

Zhou X, Michal J, Zhang L, Ding B, Lunney J, Liu B . Interferon induced IFIT family genes in host antiviral defense. Int J Biol Sci. 2013; 9(2):200-8. PMC: 3584916. DOI: 10.7150/ijbs.5613. View

Cui H, Liu J, Zhang L . The high expression of key components of inflammasome and pyroptosis might lead to severe COVID-19 infection in cancer patients. J Infect. 2022; 84(4):e19-e21. PMC: 8812082. DOI: 10.1016/j.jinf.2022.01.043. View

Thanou A, Sawalha A . SARS-CoV-2 and Systemic Lupus Erythematosus. Curr Rheumatol Rep. 2021; 23(2):8. PMC: 7842169. DOI: 10.1007/s11926-020-00973-w. View

Kong R, Sun L, Li H, Wang D . The role of NLRP3 inflammasome in the pathogenesis of rheumatic disease. Autoimmunity. 2021; 55(1):1-7. DOI: 10.1080/08916934.2021.1995860. View

Zhou G, Soufan O, Ewald J, Hancock R, Basu N, Xia J . NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis. Nucleic Acids Res. 2019; 47(W1):W234-W241. PMC: 6602507. DOI: 10.1093/nar/gkz240. View

Ugarte-Gil M, Alarcon G, Izadi Z, Duarte-Garcia A, Reategui-Sokolova C, Clarke A . Characteristics associated with poor COVID-19 outcomes in individuals with systemic lupus erythematosus: data from the COVID-19 Global Rheumatology Alliance. Ann Rheum Dis. 2022; 81(7):970-978. PMC: 8882632. DOI: 10.1136/annrheumdis-2021-221636. View

Shin J, Lee K, Joo Y, Lee J, Jeon J, Jung H . Inflammasomes and autoimmune and rheumatic diseases: A comprehensive review. J Autoimmun. 2019; 103:102299. DOI: 10.1016/j.jaut.2019.06.010. View

Yang H, Xu J, Liang X, Shi L, Wang Y . Autoimmune diseases are independently associated with COVID-19 severity: Evidence based on adjusted effect estimates. J Infect. 2020; 82(4):e23-e26. PMC: 7833739. DOI: 10.1016/j.jinf.2020.12.025. View

10.

Chang R, Chen T, Wang S, Hung Y, Chen H, Wei C . Risk of autoimmune diseases in patients with COVID-19: A retrospective cohort study. EClinicalMedicine. 2023; 56:101783. PMC: 9830133. DOI: 10.1016/j.eclinm.2022.101783. View