» Articles » PMID: 36770853

: A Factory of Nutraceutical and Food Supplements for Human Health

Overview
Journal Molecules
Publisher MDPI
Specialty Biology
Date 2023 Feb 11
PMID 36770853
Authors
Affiliations
Soon will be listed here.
Abstract

() is one of the most well-studied microalgae organisms that revealed important information for the photosynthetic and metabolic processes of plants and eukaryotes. Numerous extensive studies have also underpinned its great potential as a biochemical factory, capable of producing various highly desired molecules with a direct impact on human health and longevity. Polysaccharides, lipids, functional proteins, pigments, hormones, vaccines, and antibodies are among the valuable biomolecules that are produced spontaneously or under well-defined conditions by and can be directly linked to human nutrition and diet. The aim of this review is to highlight the recent advances in the field focusing on the most relevant applications related to the production of important biomolecules for human health that are also linked with human nutrition and diet. The limitations and challenges are critically discussed along with the potential future applications of biomass and processed products in the field of nutraceuticals and food supplements. The increasing need for high-value and low-cost biomolecules produced in an environmentally and economy sustainable manner also underline the important role of .

Citing Articles

Mutagenesis selection and large-scale cultivation of non-green for food applications.

Cao G, Hu K, Hu Z, Wu Q, Liu S, Chen X Front Nutr. 2024; 11:1456230.

PMID: 39385786 PMC: 11462061. DOI: 10.3389/fnut.2024.1456230.


Exploring Extremotolerant and Extremophilic Microalgae: New Frontiers in Sustainable Biotechnological Applications.

Rojas-Villalta D, Rojas-Rodriguez D, Villanueva-Ilama M, Guillen-Watson R, Murillo-Vega F, Gomez-Espinoza O Biology (Basel). 2024; 13(9).

PMID: 39336139 PMC: 11428398. DOI: 10.3390/biology13090712.


Extraction Optimization and Anti-Tumor Activity of Polysaccharides from .

Liang Z, Xiong L, Zang Y, Tang Z, Shang Z, Zhang J Mar Drugs. 2024; 22(8).

PMID: 39195472 PMC: 11355090. DOI: 10.3390/md22080356.


The Microalgae for Bioremediation and Bioproduct Production.

Bellido-Pedraza C, Torres M, Llamas A Cells. 2024; 13(13.

PMID: 38994989 PMC: 11240456. DOI: 10.3390/cells13131137.


Increasing lipid production in through genetic introduction for the overexpression of glyceraldehyde-3-phosphate dehydrogenase.

Shin S, Koh H, Park K, Park S, Chang Y, Kang N Front Bioeng Biotechnol. 2024; 12:1396127.

PMID: 38707501 PMC: 11066295. DOI: 10.3389/fbioe.2024.1396127.


References
1.
Merchant S, Prochnik S, Vallon O, Harris E, Karpowicz S, Witman G . The Chlamydomonas genome reveals the evolution of key animal and plant functions. Science. 2007; 318(5848):245-50. PMC: 2875087. DOI: 10.1126/science.1143609. View

2.
Antonacci A, Scognamiglio V . Biotechnological Advances in the Design of Algae-Based Biosensors. Trends Biotechnol. 2019; 38(3):334-347. DOI: 10.1016/j.tibtech.2019.10.005. View

3.
Shahidi F, Ambigaipalan P . Omega-3 Polyunsaturated Fatty Acids and Their Health Benefits. Annu Rev Food Sci Technol. 2018; 9:345-381. DOI: 10.1146/annurev-food-111317-095850. View

4.
Rasala B, Muto M, Lee P, Jager M, Cardoso R, Behnke C . Production of therapeutic proteins in algae, analysis of expression of seven human proteins in the chloroplast of Chlamydomonas reinhardtii. Plant Biotechnol J. 2010; 8(6):719-33. PMC: 2918638. DOI: 10.1111/j.1467-7652.2010.00503.x. View

5.
Manuell A, Beligni M, Elder J, Siefker D, Tran M, Weber A . Robust expression of a bioactive mammalian protein in Chlamydomonas chloroplast. Plant Biotechnol J. 2007; 5(3):402-12. DOI: 10.1111/j.1467-7652.2007.00249.x. View