Lutein Isomers: Preparation, Separation, Structure Elucidation, and Occurrence in 20 Medicinal Plants

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2023 Feb 11

PMID 36770852

Authors

Veronika Nagy

Attila Agocs

Viktoria L Balazs

Dragica Purger

Rita Filep

Viktor Sandor

Erika Turcsi

Gergely Gulyas-Fekete

Jozsef Deli

Affiliations

Soon will be listed here.

Abstract

Lutein and its -isomers occur in a lot of plants, including a variety of flowers. In this study, lutein isomers were produced via iodine-catalyzed isomerization, and four -isomers (9-, 9'-, 13-, and 13') were isolated by means of column chromatography and semipreparative HPLC. The structures of the 9'- and 13'-isomers were elucidated via NMR measurements. These compounds were used as standards for the HPLC-DAD-MS determination of the carotenoid composition of the flowers of 20 plant species, in which lutein and its geometrical isomers are the main components. The flowers showed great variation in their - and -lutein content, and also in the presence or absence of other carotenoids, such as violaxanthin, neoxanthin, β-cryptoxanthin, and β-carotene. Some of the investigated flowers were found to be rich sources of lutein without zeaxanthin.

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