Echocardiographic Parameters to Predict Malignant Events in Arrhythmic Mitral Valve Prolapse Population

Overview

Journal J Clin Med

Specialty General Medicine

Date 2023 Feb 11

PMID 36769881

Authors

Alessandro Vairo

Paolo Desalvo

Andrea Rinaudo

Francesco Piroli

Anna Tribuzio

Andrea Ballatore

Gianluca Marcelli

Lorenzo Pistelli

Veronica Dusi

Nicolo Montali

Gianluca Alunni

Cristina Barbero

Stefano Salizzoni

Marco Pocar

Mauro Rinaldi

Fiorenzo Gaita

Gaetano Maria De Ferrari

Carla Giustetto

Affiliations

Soon will be listed here.

Abstract

Bileaflet Mitral Valve Prolapse (bMVP) has been linked to major arrhythmic events and sudden cardiac death (SCD). Consistent predictors in this field are still lacking. Echocardiography is the best tool for the analysis of the prolapse and its impact on the ventricular mechanics. The aim of this study was to find new echocardiographic predictors of malignant events within an arrhythmic MVP population. We evaluated 22 patients with arrhythmic bMVP with a transthoracic echocardiogram focused on mitral valve anatomy and ventricular contraction. Six of them had major arrhythmic events that required ICD implantation (ICD-MVP group), while sixteen presented with a high arrhythmic burden without major events (A-MVP group). The best predictors of malignant events were the Anterior Mitral Leaflet (AML) greater length and greater Mechanical Dispersion (MD) of basal and mid-ventricular segments, while other significant predictors were the larger mitral valve annulus (MVA) indexed area, lower MVA anteroposterior diameter/AML length ratio, higher inferolateral basal segment S3 velocity.

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