Large Animal Models in the Study of Gynecological Diseases

Overview

Journal Front Cell Dev Biol

Specialty Cell Biology

Date 2023 Feb 9

PMID 36755972

Authors

Minghua Cui

Yuehui Liu

Xiaoping Men

Tao Li

Da Liu

Yongzhi Deng

Affiliations

Soon will be listed here.

Abstract

Gynecological diseases are a series of diseases caused by abnormalities in the female reproductive organs or breast, which endanger women's fertility and even their lives. Therefore, it is important to investigate the mechanism of occurrence and treatment of gynecological diseases. Animal models are the main objects for people to study the development of diseases and explore treatment options. Large animals, compared to small rodents, have reproductive organs with structural and physiological characteristics closer to those of humans, and are also better suited for long-term serial examinations for gynecological disease studies. This review gives examples of large animal models in gynecological diseases and provides a reference for the selection of animal models for gynecological diseases.

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