Weight Regain After Bariatric Surgery: Scope of the Problem, Causes, Prevention, and Treatment

Overview

Journal Curr Diab Rep

Publisher Current Science

Specialty Endocrinology

Date 2023 Feb 8

PMID 36752995

Authors

Sabrena F Noria

Rita D Shelby

Katelyn D Atkins

Ninh T Nguyen

Kishore M Gadde

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: Although bariatric surgery is the most effective treatment of severe obesity, a proportion of patients experience clinically significant weight regain (WR) with further out from surgery. The purpose of this review is to summarize the prevalence, predictors, and causes of weight regain.

Recent Findings: Estimating the prevalence of WR is limited by a lack of consensus on its definition. While anatomic failures such as dilated gastric fundus after sleeve gastrectomy and gastro-gastric fistula after Roux-en-Y gastric bypass can lead to WR, the most common causes appear to be dysregulated/maladaptive eating behaviors, lifestyle factors, and physiological compensatory mechanisms. To date, dietary, supportive, behavioral, and exercise interventions have not demonstrated a clinically meaningful impact on WR, and there is limited evidence for pharmacotherapy. Future studies should be aimed at better defining WR to begin to understand the etiologies. Additionally, there is a need for non-surgical interventions with demonstrated efficacy in rigorous randomized controlled trials for the prevention and reversal of WR after bariatric surgery.

Citing Articles

Optimizing Nutritional Management Before and After Bariatric Surgery: A Comprehensive Guide for Sustained Weight Loss and Metabolic Health.

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Actual weight loss trajectories after bariatric surgery compared with the SOPHIA prediction tool: An observational comparison study.

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Ring Augmentation of the Roux-en-Y Gastric Bypass: A Propensity Score Matched Analysis of 5-Year Follow-Up Results.

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