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Treponema Pallidum Immune Adherence Test for Serodiagnosis of Syphilis. 1: An Improved Method of the TPIA Test

Overview
Journal Br J Vener Dis
Specialty Infectious Diseases
Date 1978 Dec 1
PMID 367523
Citations 2
Authors
S Tanaka
T Suzuki
T Numata
Affiliations
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Abstract

Clinical investigations using the Treponema pallidum immune adherence (TPIA) test as reported by Nelson (1953) were performed only by Olansky et al in 1954. In this paper an improved method of the TPIA test is described. The test was simple to perform and was highly specific for antitreponemal antibody. Furthermore, as it was possible to use heated T. pallidum as antigen the antigen suspension could be preserved for long periods. The TPIA test for syphilis was evaluated by examining the sera from 40 healthy subjects and from 166 patients with syphilis.

Citing Articles

Low molecular weight-IgM antibody in syphilis detected by Treponema pallidum immune adherence (TPIA) test.

Tanaka S, Suzuki T, Shimada K, Nishioka K Med Microbiol Immunol. 1984; 173(3):155-65.

PMID: 6390112 DOI: 10.1007/BF02123764.

Treponema pallidum immune adherence test for serodiagnosis of syphilis. 3: Clinical significance and evaluation of treatment.

Tanaka S, Suzuki T, Numata T Br J Vener Dis. 1978; 54(6):380-5.

PMID: 367525 PMC: 1045554. DOI: 10.1136/sti.54.6.380.

References
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OLANSKY S, Harris A, Casey H . Immune-adherence test for syphilis; comparison with TPI and VDRL slide tests. Public Health Rep (1896). 1954; 69(6):521-6. PMC: 2024239. View