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Combining Analytical Epidemiology and Genomic Surveillance to Identify Risk Factors Associated with the Spread of Antimicrobial Resistance in Subsp. Serovar Heidelberg

Abstract

Antimicrobial resistance (AMR) has become a critical threat to public health worldwide. The use of antimicrobials in food and livestock agriculture, including the production of poultry, is thought to contribute to the dissemination of antibiotic resistant bacteria (ARB) and the genes and plasmids that confer the resistant phenotype (ARG). However, the relative contribution of each of these processes to the emergence of resistant pathogens in poultry production and their potential role in the transmission of resistant pathogens in human infections, requires a deeper understanding of the dynamics of ARB and ARG in food production and the factors involved in the increased risk of transmission.

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References
1.
Miller E, Elnekave E, Flores-Figueroa C, Johnson A, Kearney A, Munoz-Aguayo J . Emergence of a Novel Salmonella enterica Serotype Reading Clonal Group Is Linked to Its Expansion in Commercial Turkey Production, Resulting in Unanticipated Human Illness in North America. mSphere. 2020; 5(2). PMC: 7160679. DOI: 10.1128/mSphere.00056-20. View

2.
Pearl D, Louie M, Chui L, Dore K, Grimsrud K, Martin S . The use of randomization tests to assess the degree of similarity in PFGE patterns of E. coli O157 isolates from known outbreaks and statistical space-time clusters. Epidemiol Infect. 2006; 135(1):100-9. PMC: 2870554. DOI: 10.1017/S0950268806006650. View

3.
Falagas M, Vouloumanou E, Samonis G, Vardakas K . Fosfomycin. Clin Microbiol Rev. 2016; 29(2):321-47. PMC: 4786888. DOI: 10.1128/CMR.00068-15. View

4.
Zankari E, Hasman H, Cosentino S, Vestergaard M, Rasmussen S, Lund O . Identification of acquired antimicrobial resistance genes. J Antimicrob Chemother. 2012; 67(11):2640-4. PMC: 3468078. DOI: 10.1093/jac/dks261. View

5.
Thanner S, Drissner D, Walsh F . Antimicrobial Resistance in Agriculture. mBio. 2016; 7(2):e02227-15. PMC: 4850276. DOI: 10.1128/mBio.02227-15. View