Noise-induced Hearing Disorders: Clinical and Investigational Tools

Overview

Journal J Acoust Soc Am

Publisher American Institute of Physics

Specialty Otorhinolaryngology

Date 2023 Feb 2

PMID 36732240

Authors

Colleen G Le Prell

Odile H Clavier

Jianxin Bao

Affiliations

Soon will be listed here.

Abstract

A series of articles discussing advanced diagnostics that can be used to assess noise injury and associated noise-induced hearing disorders (NIHD) was developed under the umbrella of the United States Department of Defense Hearing Center of Excellence Pharmaceutical Interventions for Hearing Loss working group. The overarching goals of the current series were to provide insight into (1) well-established and more recently developed metrics that are sensitive for detection of cochlear pathology or diagnosis of NIHD, and (2) the tools that are available for characterizing individual noise hazard as personal exposure will vary based on distance to the sound source and placement of hearing protection devices. In addition to discussing the utility of advanced diagnostics in patient care settings, the current articles discuss the selection of outcomes and end points that can be considered for use in clinical trials investigating hearing loss prevention and hearing rehabilitation.

Citing Articles

The Role of Pericytes in Inner Ear Disorders: A Comprehensive Review.

Maniaci A, Briglia M, Allia F, Montalbano G, Romano G, Zaouali M Biology (Basel). 2024; 13(10).

PMID: 39452111 PMC: 11504721. DOI: 10.3390/biology13100802.

Ototoxicity: a high risk to auditory function that needs to be monitored in drug development.

Pasdelou M, Byelyayeva L, Malmstrom S, Pucheu S, Peytavy M, Laullier H Front Mol Neurosci. 2024; 17:1379743.

PMID: 38756707 PMC: 11096496. DOI: 10.3389/fnmol.2024.1379743.

References

Marmel F, Cortese D, Kluk K . The ongoing search for cochlear synaptopathy in humans: Masked thresholds for brief tones in Threshold Equalizing Noise. Hear Res. 2020; 392:107960. DOI: 10.1016/j.heares.2020.107960. View

Fulbright A, Le Prell C, Griffiths S, Lobarinas E . Effects of Recreational Noise on Threshold and Suprathreshold Measures of Auditory Function. Semin Hear. 2017; 38(4):298-318. PMC: 5634805. DOI: 10.1055/s-0037-1606325. View

Isherwood B, Goncalves A, Cousins R, Holme R . The global hearing therapeutic pipeline: 2021. Drug Discov Today. 2021; 27(3):912-922. DOI: 10.1016/j.drudis.2021.11.009. View

Gordon J, Griest S, Thielman E, Carlson K, Helt W, Lewis M . Audiologic characteristics in a sample of recently-separated military Veterans: The Noise Outcomes in Servicemembers Epidemiology Study (NOISE Study). Hear Res. 2016; 349:21-30. DOI: 10.1016/j.heares.2016.11.014. View

Humes L, Moore B . Estimation of all-cause noise exposure for U.S. adults from national survey data. J Acoust Soc Am. 2022; 152(6):3535. DOI: 10.1121/10.0016552. View

Baese-Berk M, Levi S, Van Engen K . Intelligibility as a measure of speech perception: Current approaches, challenges, and recommendations. J Acoust Soc Am. 2023; 153(1):68. DOI: 10.1121/10.0016806. View

King K, Brewer C . Clinical trials, ototoxicity grading scales and the audiologist's role in therapeutic decision making. Int J Audiol. 2017; 57(sup4):S89-S98. PMC: 6260812. DOI: 10.1080/14992027.2017.1417644. View

Yankaskas K . Prelude: noise-induced tinnitus and hearing loss in the military. Hear Res. 2012; 295:3-8. DOI: 10.1016/j.heares.2012.04.016. View

Kujawa S, Liberman M . Synaptopathy in the noise-exposed and aging cochlea: Primary neural degeneration in acquired sensorineural hearing loss. Hear Res. 2015; 330(Pt B):191-9. PMC: 4567542. DOI: 10.1016/j.heares.2015.02.009. View

10.

Meinke D, Norris J, Flynn B, Clavier O . Going wireless and booth-less for hearing testing in industry. Int J Audiol. 2016; 56(sup1):41-51. PMC: 5581305. DOI: 10.1080/14992027.2016.1261189. View

11.

Jafari Z, Baguley D, Kolb B, Mohajerani M . A Systematic Review and Meta-Analysis of Extended High-Frequency Hearing Thresholds in Tinnitus With a Normal Audiogram. Ear Hear. 2022; 43(6):1643-1652. DOI: 10.1097/AUD.0000000000001229. View

12.

Hammill T . A review of the progress and pitfalls of FDA policy process: Planning a pathway for pharmaceutical interventions for hearing loss development. Hear Res. 2016; 349:172-176. DOI: 10.1016/j.heares.2016.11.006. View

13.

Grose J, Buss E, Hall 3rd J . Loud Music Exposure and Cochlear Synaptopathy in Young Adults: Isolated Auditory Brainstem Response Effects but No Perceptual Consequences. Trends Hear. 2017; 21:2331216517737417. PMC: 5676494. DOI: 10.1177/2331216517737417. View

14.

Jiang M, Karasawa T, Steyger P . Aminoglycoside-Induced Cochleotoxicity: A Review. Front Cell Neurosci. 2017; 11:308. PMC: 5640705. DOI: 10.3389/fncel.2017.00308. View

15.

Bharadwaj H, Mai A, Simpson J, Choi I, Heinz M, Shinn-Cunningham B . Non-Invasive Assays of Cochlear Synaptopathy - Candidates and Considerations. Neuroscience. 2019; 407:53-66. PMC: 6513698. DOI: 10.1016/j.neuroscience.2019.02.031. View

16.

Steyger P, Cunningham L, Esquivel C, Watts K, Zuo J . Editorial: Cellular Mechanisms of Ototoxicity. Front Cell Neurosci. 2018; 12:75. PMC: 5881100. DOI: 10.3389/fncel.2018.00075. View

17.

Scheper V, Schmidtheisler M, Lasch F, von der Leyen H, Koch A, Schwieger J . Randomized placebo-controlled clinical trial investigating the effect of antioxidants and a vasodilator on overall safety and residual hearing preservation in cochlear implant patients. Trials. 2020; 21(1):643. PMC: 7362557. DOI: 10.1186/s13063-020-04522-9. View

18.

Mepani A, Kirk S, Hancock K, Bennett K, de Gruttola V, Liberman M . Middle Ear Muscle Reflex and Word Recognition in "Normal-Hearing" Adults: Evidence for Cochlear Synaptopathy?. Ear Hear. 2019; 41(1):25-38. PMC: 6934902. DOI: 10.1097/AUD.0000000000000804. View

19.

Wang Q, Yang L, Qian M, Hong Y, Wang X, Huang Z . Acute Recreational Noise-Induced Cochlear Synaptic Dysfunction in Humans With Normal Hearing: A Prospective Cohort Study. Front Neurosci. 2021; 15:659011. PMC: 8062885. DOI: 10.3389/fnins.2021.659011. View

20.

Konrad-Martin D, Poling G, Dreisbach L, Reavis K, McMillan G, Lapsley Miller J . Serial Monitoring of Otoacoustic Emissions in Clinical Trials. Otol Neurotol. 2016; 37(8):e286-94. DOI: 10.1097/MAO.0000000000001134. View