Global Epidemiological Patterns in the Burden of Main Non-Communicable Diseases, 1990-2019: Relationships With Socio-Demographic Index

Overview

Journal Int J Public Health

Specialty Public Health

Date 2023 Feb 2

PMID 36726528

Authors

Jianjun Bai

Jiaxin Cui

Fang Shi

Chuanhua Yu

Affiliations

Soon will be listed here.

Abstract

This study aimed to analyze spatio-temporal patterns of the global burden caused by main NCDs along the socio-economic development. We extracted relevant data from GBD 2019. The estimated annual percentage changes, quantile regression and limited cubic splines were adopted to estimate temporal trends and relationships with socio-demographic index. NCDs accounted for 74.36% of global all-cause deaths in 2019. The main NCDs diseases were estimated for cardiovascular diseases, neoplasms, and chronic respiratory diseases, with deaths of 18.56 (17.08-19.72) million, 10.08 (9.41-10.66) million and 3.97 (3.58-4.30) million, respectively. The death burden of three diseases gradually decreased globally over time. Regional and sex variations existed worldwide. Besides, the death burden of CVD showed the inverted U-shaped associations with SDI, while neoplasms were positively correlated with SDI, and CRD showed the negative association. NCDs remain a crucial public health issue worldwide, though several favorable trends of CVD, neoplasms and CRD were observed. Regional and sex disparities still existed. Public health managers should execute more targeted programs to lessen NCDs burden, predominantly among lower SDI countries.

Citing Articles

Lip and oral cavity cancer in Iran from 1990 to 2019 based on the global burden of disease study.

Roghanizadeh L, Atarbashi-Moghadam S, Masaebi F, Baghban A Sci Rep. 2025; 15(1):7389.

PMID: 40032973 PMC: 11876645. DOI: 10.1038/s41598-025-92090-w.

Global burden of reported lower respiratory system fungal infection.

Wang Z, Pan M, Zhu J Front Cell Infect Microbiol. 2025; 15:1542922.

PMID: 40028180 PMC: 11868289. DOI: 10.3389/fcimb.2025.1542922.

Global, regional, and national burden of cardiovascular disease attributable to kidney dysfunction (1990-2021) with projections to 2050: analysis of the 2021 Global Burden of Disease study.

Zhang T, Li T, Jin P Ren Fail. 2025; 47(1):2472039.

PMID: 40015719 PMC: 11869346. DOI: 10.1080/0886022X.2025.2472039.

Urinary Biomarkers Of Kidney Function As Predictors Of Cardiovascular Health: A Systematic Review.

Degenaar A, Kruger R, Jacobs A, Mels C Curr Hypertens Rep. 2025; 27(1):11.

PMID: 39982568 PMC: 11845436. DOI: 10.1007/s11906-025-01328-5.

The changing burden of gout in adults aged 70 and above based on the global burden of disease 2019.

Yang Y, Liu Z Front Public Health. 2025; 13:1455726.

PMID: 39980931 PMC: 11840442. DOI: 10.3389/fpubh.2025.1455726.

References

. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018; 392(10159):1736-1788. PMC: 6227606. DOI: 10.1016/S0140-6736(18)32203-7. View

Fitzmaurice C, Allen C, Barber R, Barregard L, Bhutta Z, Brenner H . Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015: A Systematic Analysis for the Global Burden of Disease Study. JAMA Oncol. 2016; 3(4):524-548. PMC: 6103527. DOI: 10.1001/jamaoncol.2016.5688. View

Lundqvist A, Andersson E, Ahlberg I, Nilbert M, Gerdtham U . Socioeconomic inequalities in breast cancer incidence and mortality in Europe-a systematic review and meta-analysis. Eur J Public Health. 2016; 26(5):804-813. PMC: 5054273. DOI: 10.1093/eurpub/ckw070. View

McBride B, Hawkes S, Buse K . Soft power and global health: the sustainable development goals (SDGs) era health agendas of the G7, G20 and BRICS. BMC Public Health. 2019; 19(1):815. PMC: 6591917. DOI: 10.1186/s12889-019-7114-5. View

Siegel R, Miller K, Jemal A . Cancer statistics, 2019. CA Cancer J Clin. 2019; 69(1):7-34. DOI: 10.3322/caac.21551. View

Checkley W, Ghannem H, Irazola V, Kimaiyo S, Levitt N, Miranda J . Management of NCD in low- and middle-income countries. Glob Heart. 2015; 9(4):431-43. PMC: 4299752. DOI: 10.1016/j.gheart.2014.11.003. View

. Evolution and patterns of global health financing 1995-2014: development assistance for health, and government, prepaid private, and out-of-pocket health spending in 184 countries. Lancet. 2017; 389(10083):1981-2004. PMC: 5440770. DOI: 10.1016/S0140-6736(17)30874-7. View

Dye C . After 2015: infectious diseases in a new era of health and development. Philos Trans R Soc Lond B Biol Sci. 2014; 369(1645):20130426. PMC: 4024220. DOI: 10.1098/rstb.2013.0426. View

Bollyky T, Templin T, Cohen M, Dieleman J . Lower-Income Countries That Face The Most Rapid Shift In Noncommunicable Disease Burden Are Also The Least Prepared. Health Aff (Millwood). 2017; 36(11):1866-1875. PMC: 7705176. DOI: 10.1377/hlthaff.2017.0708. View

10.

Plummer M, de Martel C, Vignat J, Ferlay J, Bray F, Franceschi S . Global burden of cancers attributable to infections in 2012: a synthetic analysis. Lancet Glob Health. 2016; 4(9):e609-16. DOI: 10.1016/S2214-109X(16)30143-7. View

11.

. Five insights from the Global Burden of Disease Study 2019. Lancet. 2020; 396(10258):1135-1159. PMC: 7116361. DOI: 10.1016/S0140-6736(20)31404-5. View

12.

Roth G, Johnson C, Abajobir A, Abd-Allah F, Abera S, Abyu G . Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015. J Am Coll Cardiol. 2017; 70(1):1-25. PMC: 5491406. DOI: 10.1016/j.jacc.2017.04.052. View

13.

Farcomeni A, Geraci M . Multistate quantile regression models. Stat Med. 2019; 39(1):45-56. DOI: 10.1002/sim.8393. View

14.

. Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016; 388(10053):1603-1658. PMC: 5388857. DOI: 10.1016/S0140-6736(16)31460-X. View

15.

. Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020; 396(10258):1223-1249. PMC: 7566194. DOI: 10.1016/S0140-6736(20)30752-2. View

16.

Alleyne G, Binagwaho A, Haines A, Jahan S, Nugent R, Rojhani A . Embedding non-communicable diseases in the post-2015 development agenda. Lancet. 2013; 381(9866):566-74. DOI: 10.1016/S0140-6736(12)61806-6. View

17.

Xu Y, Wang A, Lin X, Xu J, Shan Y, Pan X . Global burden and gender disparity of vision loss associated with diabetes retinopathy. Acta Ophthalmol. 2020; 99(4):431-440. DOI: 10.1111/aos.14644. View

18.

Thomas H, Diamond J, Vieco A, Chaudhuri S, Shinnar E, Cromer S . Global Atlas of Cardiovascular Disease 2000-2016: The Path to Prevention and Control. Glob Heart. 2018; 13(3):143-163. DOI: 10.1016/j.gheart.2018.09.511. View

19.

Omran A . The epidemiologic transition: a theory of the epidemiology of population change. 1971. Milbank Q. 2005; 83(4):731-57. PMC: 2690264. DOI: 10.1111/j.1468-0009.2005.00398.x. View

20.

Reiner Jr R, Olsen H, Ikeda C, Echko M, Ballestreros K, Manguerra H . Diseases, Injuries, and Risk Factors in Child and Adolescent Health, 1990 to 2017: Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2017 Study. JAMA Pediatr. 2019; 173(6):e190337. PMC: 6547084. DOI: 10.1001/jamapediatrics.2019.0337. View