Internal Neural States Influence the Short-term Effect of Monocular Deprivation in Human Adults

Overview

Journal Elife

Specialty Biology

Date 2023 Jan 27

PMID 36705563

Authors

Yiya Chen

Yige Gao

Zhifen He

Zhouyuan Sun

Yu Mao

Robert F Hess

Peng Zhang

Jiawei Zhou

Affiliations

Soon will be listed here.

Abstract

The adult human visual system maintains the ability to be altered by sensory deprivation. What has not been considered is whether the internal neural states modulate visual sensitivity to short-term monocular deprivation. In this study we manipulated the internal neural state and reported changes in intrinsic neural oscillations with a patched eye open or closed. We investigated the influence of eye open/eye closure on the unpatched eye's contrast sensitivity and ocular dominance (OD) shifts induced by short-term monocular deprivation. The results demonstrate that internal neural states influence not only baseline contrast sensitivity but also the extent to which the adult visual system can undergo changes in ocular dominance.

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