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Identification of Optimal Surgical Plan for Treatment of Extraocular Muscle Damage in Thyroid Eye Disease Patients Based on Computational Biomechanics

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Date 2023 Jan 27
PMID 36704311
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Abstract

This study replicated the behavior of intraorbital tissue in patients with thyroid eye disease (TED) based on finite element analysis for general orbital decompression risk evaluation in thyroid eye disease patients. The orbit and intraorbital tissues of thyroid eye disease patients who underwent orbital decompression were modeled as finite element models. The stress was examined at specific locations of the removed orbital wall of a thyroid eye disease patient with undergone orbital decompression, and its variation was analyzed as a function of the shape and dimension (to be removed). As a result, in orbital decompression surgery which removes the orbital wall in a rectangular shape, the stress at the orbital wall decreased as the width and depth of the removed orbital wall increased. In addition, in the case of orbital decompression, it can be seen that the chamfered model compared to the non-chamfered model (a form of general orbital decompression) have the stress reduction rate from 11.08% to 97.88%. It is inferred that if orbital decompression surgery considering the chamfered model is performed on an actual thyroid eye disease patient, it is expected that the damage to the extraocular muscle caused by the removed orbital wall will be reduced.

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References
1.
Genere N, Stan M . Current and Emerging Treatment Strategies for Graves' Orbitopathy. Drugs. 2019; 79(2):109-124. DOI: 10.1007/s40265-018-1045-9. View

2.
Cirovic S, Bhola R, Hose D, Howard I, Lawford P, Marr J . Computer modelling study of the mechanism of optic nerve injury in blunt trauma. Br J Ophthalmol. 2006; 90(6):778-83. PMC: 1860230. DOI: 10.1136/bjo.2005.086538. View

3.
Schutte S, van den Bedem S, van Keulen F, van der Helm F, Simonsz H . A finite-element analysis model of orbital biomechanics. Vision Res. 2006; 46(11):1724-31. DOI: 10.1016/j.visres.2005.11.022. View

4.
Hernandez-Garcia E, San-Roman J, Gonzalez R, Nogueira A, Genol I, Stoica B . Balanced (endoscopic medial and transcutaneous lateral) orbital decompression in Graves' orbitopathy. Acta Otolaryngol. 2017; 137(11):1183-1187. DOI: 10.1080/00016489.2017.1354394. View

5.
Gontarz-Nowak K, Szychlinska M, Matuszewski W, Stefanowicz-Rutkowska M, Bandurska-Stankiewicz E . Current Knowledge on Graves' Orbitopathy. J Clin Med. 2020; 10(1). PMC: 7793490. DOI: 10.3390/jcm10010016. View