Recent Advances in Optical Elastography and Emerging Opportunities in the Basic Sciences and Translational Medicine [Invited]

Overview

Journal Biomed Opt Express

Specialty Radiology

Date 2023 Jan 26

PMID 36698669

Authors

Nichaluk Leartprapun

Steven G Adie

Affiliations

Soon will be listed here.

Abstract

Optical elastography offers a rich body of imaging capabilities that can serve as a bridge between organ-level medical elastography and single-molecule biophysics. We review the methodologies and recent developments in optical coherence elastography, Brillouin microscopy, optical microrheology, and photoacoustic elastography. With an outlook toward maximizing the basic science and translational clinical impact of optical elastography technologies, we discuss potential ways that these techniques can integrate not only with each other, but also with supporting technologies and capabilities in other biomedical fields. By embracing cross-modality and cross-disciplinary interactions with these parallel fields, optical elastography can greatly increase its potential to drive new discoveries in the biomedical sciences as well as the development of novel biomechanics-based clinical diagnostics and therapeutics.

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