A Self-powered Multifunctional Dressing for Active Infection Prevention and Accelerated Wound Healing

Overview

Journal Sci Adv

Specialties Biology
Science

Date 2023 Jan 25

PMID 36696504

Authors

Snigdha Roy Barman

Shuen-Wen Chan

Fu-Cheng Kao

Hsuan-Yu Ho

Imran Khan

Arnab Pal

Chih-Ching Huang

Zong-Hong Lin

Affiliations

Soon will be listed here.

Abstract

Interruption of the wound healing process due to pathogenic infection remains a major health care challenge. The existing methods for wound management require power sources that hinder their utilization outside of clinical settings. Here, a next generation of wearable self-powered wound dressing is developed, which can be activated by diverse stimuli from the patient's body and provide on-demand treatment for both normal and infected wounds. The highly tunable dressing is composed of thermocatalytic bismuth telluride nanoplates (BiTe NPs) functionalized onto carbon fiber fabric electrodes and triggered by the surrounding temperature difference to controllably generate hydrogen peroxide to effectively inhibit bacterial growth at the wound site. The integrated electrodes are connected to a wearable triboelectric nanogenerator (TENG) to provide electrical stimulation for accelerated wound closure by enhancing cellular proliferation, migration, and angiogenesis. The reported self-powered dressing holds great potential in facilitating personalized and user-friendly wound care with improved healing outcomes.

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