The Effect of Nifedipine on Cystoscopy-induced Autonomic Hyperreflexia in Patients with High Spinal Cord Injuries
Overview
Authors
Affiliations
We evaluated the ability of the calcium channel blocker nifedipine to control autonomic hyperreflexia during cystoscopy in 7 patients with cervical spinal cord injuries. Nifedipine (10 mg.) alleviated autonomic hyperreflexia when given sublingually during cystoscopy and prevented autonomic hyperreflexia when given orally 30 minutes before cystoscopy. No adverse drug effects were observed.
Aziz Rizk A, Saad M, Singh M, Schaller B, Venkatraghavan L, Chowdhury T Front Med (Lausanne). 2022; 9:852892.
PMID: 35419369 PMC: 8996073. DOI: 10.3389/fmed.2022.852892.
Autonomic dysreflexia: a cardiovascular disorder following spinal cord injury.
Sharif H, Hou S Neural Regen Res. 2017; 12(9):1390-1400.
PMID: 29089975 PMC: 5649450. DOI: 10.4103/1673-5374.215241.
Autonomic dysreflexia after spinal cord injury: Systemic pathophysiology and methods of management.
Eldahan K, Rabchevsky A Auton Neurosci. 2017; 209:59-70.
PMID: 28506502 PMC: 5677594. DOI: 10.1016/j.autneu.2017.05.002.
Iatrogenic urological triggers of autonomic dysreflexia: a systematic review.
Liu N, Zhou M, Biering-Sorensen F, Krassioukov A Spinal Cord. 2015; 53(7):500-9.
PMID: 25800696 DOI: 10.1038/sc.2015.39.
Vaidyanathan S, Soni B, Selmi F, Singh G, Esanu C, Hughes P Patient Saf Surg. 2012; 6:3.
PMID: 22348226 PMC: 3296613. DOI: 10.1186/1754-9493-6-3.