Effect of Transcutaneous Electrical Acupoint Stimulation on Bone Metabolism in Patients with Immobilisation After Foot and Ankle Fracture Surgery: a Randomised Controlled Trial Study Protocol

Overview

Journal BMJ Open

Specialty General Medicine

Date 2023 Jan 23

PMID 36691208

Authors

Shiqi Guo

Guozhen Zhao

Xue-Ming Chen

Ying Xue

Xia-Li Ouyang

Jin-Yi Liu

Yue-Ping Huang

Ya-Jie Liu

Qin Yao

Li Han

Chun-Hui Zhang

Bo Li

Qi Wang

Baixiao Zhao

Affiliations

Soon will be listed here.

Abstract

Introduction: Fracture is a disease with a high incidence worldwide. Foot and ankle fractures are common among fractures of the lower extremities. Foot and ankle fractures usually require surgical fixation and a period of fixed treatment, which can lead to decreased bone density. Although transcutaneous electrical acupoint stimulation (TEAS) is widely used for movement system diseases, there is minimal evidence to show the effectiveness of TEAS on patients after surgical fixation of ankle and foot fractures. This trial aims to evaluate whether TEAS can reduce bone loss in patients with immobilisation after ankle and foot fractures.

Methods And Analysis: A randomised controlled trial will be conducted in which 60 patients will be randomly divided into two groups: (a) the control group will be treated according to the routine procedures of basic orthopaedics treatment; (b) in the treatment group, bilateral SP36, BL23 and ST36 will be performed on the basis of the control group, and the test will be performed for 30 min every other day for a total of 8 weeks. Bone turnover markers will be used as primary outcome. Secondary outcomes are composed of blood phosphorus, blood calcium and bone mineral density. Treatment safety will be monitored and recorded.

Ethics And Dissemination: This trial is approved by the Ethics Committee of Beijing University of Chinese Medicine (2020BZYLL0611) and the Ethics Committee of Beijing Luhe Hospital (2020-LHKY-055-02), and inpatients who meet the following diagnostic and inclusion criteria are eligible to participate in this study.

Trial Registration Number: ChiCTR 2000039944.

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