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Comparative Evaluation of Antimicrobial Efficacy of Herbal Formulations of Septilin and Triphala with Conventional 2% Chlorhexidine on Root Canal and Oral Commensal Bacteria Using Kirby Bauer Method: An Study

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Specialty Dentistry
Date 2023 Jan 23
PMID 36686996
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Abstract

Background: Endodontic flareups are always very difficult to treat because of reasons like drug resistance previously sodium hypochlorite and chlorhexidine have been used in the literature but with advancements newer materials like herbal products have been tried for this purpose. Thus, present vitro study was conducted to comparatively evaluate the efficacy of herbal formulations on commensals of oral cavity and root canal.

Materials And Methods: In this study antimicrobial efficacy of chlorhexidine 2%, Septilin and Triphala wer evaluated with the help of Kirby Bauer test. The microorganisms used were and . The samples were placed in standardized wells and were subjected to incubation. Subsequently zones of inhibition were measured with the help of a caliper. One-factor analysis of variance, Tukey's least significant difference test and Student's independent -test were performed to find a significant difference ( < 0.05) in the two groups.

Results: For chlorhexidine in mean antibacterial efficacy was 11.10 ± 1.25 and in 10.0 ± 1.33. The value for was lesser in Triphala with a value of 10.35 ± 1.63 and in mean value was 9.05 ± 1.27. For Septilin the mean for was 10.40 ± 1.04, and the mean antibacterial efficacy in was 9.65 ± 1.38.

Conclusion: Septilin and Triphala showed remarkable efficacy concerning zones of inhibition. These herbal formulations have tremendous potential to be used as adjuncts to traditional disinfection modalities though it has scope of further research.

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References
1.
Shetty S, Bose A, Sridharan S, Satyanarayana A, Rahul A . A clinico-biochemical evaluation of the role of a herbal (Ayurvedic) immunomodulator in chronic periodontal disease: a pilot study. Oral Health Dent Manag. 2013; 12(2):95-104. View

2.
Rath P, Yiu C, Matinlinna J, Kishen A, Neelakantan P . The effect of root canal irrigants on dentin: a focused review. Restor Dent Endod. 2020; 45(3):e39. PMC: 7431934. DOI: 10.5395/rde.2020.45.e39. View

3.
Inoue B, Streit S, Dos Santos Schneider A, Meier M . Bioactive bacterial cellulose membrane with prolonged release of chlorhexidine for dental medical application. Int J Biol Macromol. 2020; 148:1098-1108. DOI: 10.1016/j.ijbiomac.2020.01.036. View

4.
Eick S . Biofilm Models for the Evaluation of Dental Treatment. Monogr Oral Sci. 2021; 29:38-52. DOI: 10.1159/000510198. View

5.
Prada I, Mico-Munoz P, Giner-Lluesma T, Mico-Martinez P, Muwaquet-Rodriguez S, Albero-Monteagudo A . Update of the therapeutic planning of irrigation and intracanal medication in root canal treatment. A literature review. J Clin Exp Dent. 2019; 11(2):e185-e193. PMC: 6383907. DOI: 10.4317/jced.55560. View