Synthesis of Benzo[]furans from Alkynyl Sulfoxides and Phenols by the Interrupted Pummerer Reaction

Overview

Journal RSC Adv

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2023 Jan 23

PMID 36686947

Authors

Akihiro Kobayashi

Tsubasa Matsuzawa

Takamitsu Hosoya

Suguru Yoshida

Affiliations

Soon will be listed here.

Abstract

The interrupted Pummerer reaction of alkynyl sulfoxides with phenols is disclosed. A wide range of benzo[]furans were efficiently synthesized through unexplored electrophilic activation of the electron-deficient alkynyl sulfinyl group. Based on the good availability of alkynyl sulfoxides, we successfully prepared various functionalized benzo[]furans from readily available alkynes, thiosulfonates, and phenols.

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